ArticleBrain and behavior2024
The Resting-State Activities of the Angular Gyrus and the Micturition Desire-Awakening Function in Children With and Without Enuresis.
Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMicturition desire-awakening (MDA) function plays a pivotal role in the development of primary nocturnal enuresis (PNE); however, its neural correlates remain largely unexplored. Consequently, this study aimed to identify specific brain regional activities associated with MDA function.
methodsNeuroimaging data were collected from 173 children with varying MDA functional grade scores at the Department of Developmental and Behavioral Pediatrics, Shanghai Children's Medical Center, from July 2018 to November 2022. Resting-state images were analyzed using whole-brain correlation techniques and AlphaSim correction to identify brain regional activities and resting-state functional connectivity (RSFC) associated with MDA functional grade scores.
resultsWhole-brain correlation analysis demonstrated that the fractional amplitude of low-frequency fluctuations in the right angular gyrus (AG) exhibited a negative correlation with MDA functional grade scores (r
conclusionThese findings provide preliminary insights into the neural underpinnings of MDA functionality.
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