ArticleActa neurochirurgica2024
Neuroplasticity in glioblastoma: there is more to plasticity than just low grade glioma.
Article in Acta neurochirurgica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Awake craniotomy and language assessment in deaf patients: a systematic review of feasibility, communication strategies, and outcomes.Journal of neuro-oncology · 2026Pooled it
- StructuralBrain & spine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuroplasticity is well established in low grade glioma patients. Less is known about functional plasticity in glioblastomas. A 56-year-old lady presented with a recurrent speech deficit seventeen months after her initial craniotomy for a language eloquent glioblastoma (GBM). Pre-operative navigated trans-cranial magnetic stimulation (n-TMS) for language mapping, tractography and intra-operative language mapping were performed. During her second admission, preoperative n-TMS revealed positive responses anterior and posterior to the tumour recurrence. Tractography revealed a decrease in the anterior extension of the Arcuate Fasciculus (AF) in the inferior frontal gyrus and a more anterior component of the Frontal-Aslant Tract (FAT) showed anterior to the tumour itself. A second resection was carried out and the patient was discharged with no language deficit for second line treatment with Lomustine. Intraoperatively, speech arrest was found in a new position posterior to the previous surgical cavity and away from tumour recurrence (where speech arrest was previously located). This case report shows language function neuroplasticity in glioblastoma. This is supported by preoperative cortical and subcortical mapping.
Indexed as
Identifiers
39668322What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.