ArticleAnnals of surgical oncology2025
Analysis the Burden of Breast Cancer Among Adolescents and Young Adults Using the Global Burden of Disease 2021.
Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Increasing Burden of Early-Onset Cancers: Disentangling the Contributions of Changes in Risk from Demographic Shifts.Cancer research communications · 2026Article
- Global trends and projections of early-onset CKD burden: a GBD 2021 analysis.Clinical kidney journal · 2026Article
- Population Dynamic Projections of Near Vision Loss and Refractive Disorders in China and the G20 From 1990 to 2038.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Trends and projections of IHD burden attributable to dietary high sodium and kidney dysfunction in G20 countries, 1990-2050.PloS one · 2026Article
- Global, regional and national burden of intracerebral hemorrhage attributable to dietary and metabolic risks from 1990 to 2021 and projections to 2050: a systematic analysis based on the Global Burden of Disease 2021 comparative risk assessment framework.European journal of medical research · 2025Article
- Global, regional and national burdens of gastroesophageal reflux disease from 1990 to 2021 and projections to 2050: a finding from the global burden of disease study 2021.BMC public health · 2025Article
- Trends in cancer burden for adolescents and young adults in China from 1990 to 2021.BMC cancer · 2025Article
- Sweets consumption and breast cancer risk among women in yemen: a matched case control study.BMC cancer · 2025Article
- Global, regional, and national burden of acute hepatitis (1990-2021): a systematic analysis of the global burden of disease in 2021.Frontiers in medicine · 2025Article
- Liver cancer burden attributable to high body mass index and high fasting plasma glucose in BRICS countries (1990-2021): a Global Burden of Disease 2021 analysis with projections to 2050.Frontiers in oncology · 2025Article
- Global, regional and national burden of diabetes mellitus type 2 attributable to low physical activity from 1990 to 2021 and projections to 2050: a finding from the global burden of disease study 2021.Frontiers in clinical diabetes and healthcare · 2025Article
- A comprehensive analysis of vitamin a deficiency burden and trends: insights from the global burden of disease study 2021 and future predictions to 2050.Frontiers in nutrition · 2025Article
- ASO Author Reflections: Advancing Gastric Cancer Treatment Through HIPEC-Current Insights and Future Directions.Annals of surgical oncology · 2025Article
- Global burden and developments in pre- and post-menopausal estrogen-related cancer from 1990 to 2021, with estimates for 2035.Archives of medical science : AMS · 2025Article
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9 authors.
Funding
Abstract
backgroundUnique features and worse outcomes have been reported for breast cancers among adolescents and young adults (AYAs; age 15-39 years). However, there are few up-to-date and comprehensive data to analyze the disease burden of AYA breast cancer. PATIENTS AND
methodsThe data of incidence, deaths, and disability-adjusted life years (DALYs) owing to breast cancer was obtained from the Global Burden of Disease (GBD) 2021. We computed estimated annual percentage changes (EAPCs) of each indicator to capture the secular trend in breast cancer and conducted a decomposition analysis to examine factors behind DALYs changes. We also predicted the incident cases, deaths and DALYs to 2044.
resultsFrom 1990 to 2021, the age-standardized incidence rate (ASIR) experienced an increasing trend globally [EAPC: 0.87, 95% confidence interval (CI) 0.77-0.97]. The age-standardized rates (ASRs) of male AYAs breast cancer were all on the rise. The most significant increase trends in ASRs among female AYAs occurred in North Africa and Middle East, while male AYAs showed the highest increases in East Asia. Population growth contributed the most to the growth of DALYs in East Asia. Frontier analysis showed that despite limited resources, some underdeveloped countries still exhibit superior performance, while other countries with higher sociodemographic index have great room for improvement.
conclusionsThe global burden of AYAs breast cancer is grim, especially in North Africa and Middle East. The significant increase in male AYAs breast cancer burden, targeted prevention strategies may need to be developed for AYAs breast cancer by sex and countries.
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