Evidence map›Paper›PMID 39668307›Full record

ArticleInternational ophthalmology2024

Mobile unidirectional airflow device reduces air contamination in an intravitreal outpatient clean room setting.

Tito Fiore, Nicola De Santi, Donatella Pietrella, Mariella Barcaccia, Melissa Ida Palmieri, Marco Lupidi, Cesare Mariotti, Carlo Cagini

Abstract read
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In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tito FioreDepartment of Medicine Surgical, Section of Ophthalmology, University of Perugia, S. Maria Della Misericordia Hospital, 06156, Perugia, Italy.
Nicola De SantiDepartment of Medicine Surgical, Section of Ophthalmology, University of Perugia, S. Maria Della Misericordia Hospital, 06156, Perugia, Italy. nicola.desanti@hotmail.it.
Donatella PietrellaDepartment of Medicine and Surgery, Medical Microbiology Section, University of Perugia, 06156, Perugia, Italy.
Mariella BarcacciaDepartment of Medicine and Surgery, Medical Microbiology Section, University of Perugia, 06156, Perugia, Italy.
Melissa Ida PalmieriDepartment of Medicine and Surgery, Medical Microbiology Section, University of Perugia, 06156, Perugia, Italy.
Marco LupidiDepartment of Experimental and Clinical Medicine, Eye Clinic, Polytechnic University of Marche, Ancona, Italy.
Cesare MariottiDepartment of Experimental and Clinical Medicine, Eye Clinic, Polytechnic University of Marche, Ancona, Italy.
Carlo CaginiDepartment of Medicine Surgical, Section of Ophthalmology, University of Perugia, S. Maria Della Misericordia Hospital, 06156, Perugia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate and compare the mycobacterial load using a mobile laminar airflow (LAF) device in an IVI-dedicated outpatient clean room (OCR) without ventilation systems and in a hospital-based operating theatre (HOT).

methodsThis case-control study was conducted in 2 different settings: OCR and HOT during a series of intravitreal injections (IVIs). The Air Microbial analysis was performed using a Surface Air System instrument at three different moments during the IVI sessions in both settings: at the operative site (OS), four meters from the OS (DOS) and in the disinfection room (DR).

resultsAt the OS in the OCR, the microbial load was 20.33 ± 16.51 CFU/m

conclusionsThis standardized sterile technique in an OCR setting, with a mobile LAF, reduces the microbial colonies to levels that are safe and comparable to those recorded in the HOT setting, thus potentially improving the safety of IVIs in an OCR setting.

Indexed as

Air MicrobiologyIntravitreal InjectionsCase-Control StudiesEnvironment, ControlledHumansOperating RoomsVentilationAirflow deviceContaminationIntravitreal injectionsPostinjection endophthalmitis

Identifiers

PMID39668307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.