Evidence map›Paper›PMID 39668263›Full record

ReviewWorld journal of urology2024

Comprehensive analysis of the bacterial spectrum for enhanced clinical insight in microbial ureteral stent colonization, uncomplicated urinary tract infections and catheter-associated urinary tract infections: a principal component analysis-based literature review.

Matilde Lepori, Olivier Braissant, Gernot Bonkat, Malte Rieken

Abstract readReview
In one paragraph

Review in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matilde LeporiDepartment of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, 4123, Allschwil, Switzerland. matilde.lepori@stud.unibas.ch.
Olivier BraissantDepartment of Biomedical Engineering, University of Basel, Hegenheimermattweg 167B/C, 4123, Allschwil, Switzerland.
Gernot BonkatAlta Uro AG, Centralbahnplatz 6, 4051, Basel, Switzerland.
Malte RiekenAlta Uro AG, Centralbahnplatz 6, 4051, Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeControversies exist regarding the prevailing spectrum of microorganisms in microbial ureteral stent colonization (MUSC) and their clinical significance. The aim of this comprehensive review is to determine the predominant microbial spectrum in patients with an indwelling ureteral stent in comparison to catheter-associated urinary tract infections (CAUTI) and uncomplicated urinary tract infections (UTI).

methodsGoogle scholar, PubMed, Embase, Medline, and Cochrane literature databases were searched from inception to April 2022 to identify manuscripts on MUSC, uncomplicated UTI and CAUTI. A principal component analysis (PCA) was performed to identify patterns of the pathogen spectrum of the different groups.

resultsWe included 29 studies on MUSC, 28 studies on uncomplicated UTI and 23 CAUTI studies. The proportion of Staphylococci, Enterococci and Candida were significantly higher in MUSC and stent associated bacteriuria compared to their proportion in uncomplicated UTIs where E. coli dominates. By comparing MUSC, CAUTI and UTI with a PCA, the detected pathogen spectrum exhibited clearly distinguishable trends in the frequency of the main isolated pathogens influencing these three groups of urinary tract infections. With respect to MUSC and UTI, their 95% confidence interval ellipse only showed minimal overlap emphasizing that the spectrum of pathogens in the two groups is clearly distinct.

conclusionsThe frequency of detection of Staphylococci, Enterococci and Candida is more common in MUSC as compared to UTI. Thus, patients with indwelling ureteral stents should undergo an antimicrobial prophylaxis targeting this microbial spectrum in case of further surgery.

Indexed as

Catheter-Related InfectionsPrincipal Component AnalysisStentsUreterUrinary Tract InfectionsHumansProsthesis-Related InfectionsBacteriuriaUreteral catheterizationUreteroscopyUrinary tract infections

Identifiers

PMID39668263
PMCPMC11638318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.