ArticleArchives of gynecology and obstetrics2025
Predicting the risk of cesarean hysterectomy in the management of placenta accreta spectrum disorders: a new model based on clinical findings and ultrasonography.
Article in Archives of gynecology and obstetrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Prenatal predictors of severe maternal outcomes in placenta accreta spectrum: A multicenter cohort study in China.European journal of obstetrics & gynecology and reproductive biology: X · 2026Article
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7 authors.
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Abstract
purposeTo develop a nomogram to predict the probability of cesarean hysterectomy (CH) in placenta accreta spectrum disorders (PASD) patients.
methodsData from 520 patients who underwent surgery with a preliminary diagnosis of PASD at a tertiary center in southeast Turkey between 2013 and 2023 were collected, and 302 patients were included in the study. A predictive model based on clinical and ultrasonographic variables was developed using penalized maximum likelihood estimation (PMLE) regression analysis.
resultsMaternal age (aOR = 1.22, 95% CI 1.08-1.44, p = 0.001) and prior uterine surgeries (aOR = 3.18, 95% CI 1.57-8.29, p = 0.001) were identified as demographic factors with an increased likelihood of CH in the nomogram, and advanced gestational weeks demonstrated a negative correlation (aOR: 0.78, 95% CI 0.56-1.02, p = 0.07). Regarding the ultrasonographic findings, the presence of the "multiple lacunae within the placenta" (aOR = 48.53, 95% CI 18.42-257.40, p < 0.001) and the "anterior placental location" (aOR = 9.60, 95% CI 2.96-50.76, p < 0.001) significantly increased the probability of CH. In addition, "hypervascularization on Doppler flow with irregularity in the line between the bladder and uterine serosa" (aOR = 7.90, 95% CI 2.66-35.12, p < 0.001) and the "retroplacental myometrial thickness of < 1 mm" (aOR = 2.49, 95% CI 0.89-8.27, p = 0.08) were related to the probability of CH. Harrell's C-index was 0.974, and the kappa value was 0.819 for the prediction model's performance evaluation.
conclusionWe developed a nomogram to predict the probability of cesarean hysterectomy in patients with PASD, incorporating maternal age, gestational weeks, prior uterine surgeries, ultrasound findings, and placental location. The most closely associated findings with CH in patients with PASD were the presence of multiple placental lacunae and the anterior location of the placenta.
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