Evidence map›Paper›PMID 39667931›Full record

ArticleStructure (London, England : 1993)2025

Structural insights into subunit-dependent functional regulation in epithelial sodium channels.

Alexandra Houser, Isabelle Baconguis

Abstract read
In one paragraph

Article in Structure (London, England : 1993), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Acid-sensing ion channel 2a assembles with epithelial NaThe Journal of biological chemistry · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Alexandra HouserNeuroscience Graduate Program, Oregon Health & Science University, Portland, OR 97239, USA.
Isabelle BaconguisVollum Institute, Oregon Health & Science University, Portland, OR 97239, USA. Electronic address: bacongui@ohsu.edu.

Funding

Pacific Northwest Center for Cryo-EM - Screening supplementU24GM129547 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI EVANS, JAMES E, GOUAUX, JAMES E · 2018 to 2023
$54.8M
Elucidating the molecular mechanism of ENaC functionR01GM138862 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BACONGUIS, ISABELLE RHYSSA JOE EDURIA · 2020 to 2023
$1.4M
NIGMS NIH HHS R01 GM138862NIGMS NIH HHS U24 GM129547
6 · The paper itself

Abstract

Epithelial sodium channels (ENaCs) play a crucial role in Na

Indexed as

Epithelial Sodium ChannelsProtein SubunitsCryoelectron MicroscopyHumansModels, MolecularProtein MultimerizationEpithelial Sodium ChannelsProtein Subunitschannel assemblycryo-EMENaCheteromeric complexion channelstructural biologysubunit stoichiometryZn(2+) modulationδ subunit

Identifiers

PMID39667931
PMCPMC11805665

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.