ReviewJournal of pediatric and adolescent gynecology2025
The Vaginal Microbiome and Reproductive Health in Adolescents and Adults.
Review in Journal of pediatric and adolescent gynecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Vaginal microbiomes and their pertinent social context: a microbial ecological review proffering AMR-STI acquisition and emergence.Biology of sex differences · 2026Review
- The profiles of vaginal microbiota in fertile and infertile Thai women.BMC women's health · 2026Article
- Timing of menstrual cups to prevent transition from optimal to not optimal vaginal microbiome community state type: Results from a 6.5-year prospective observational cohort.Research square · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
STUDY
objectiveThe aim of this paper is to review our understanding of the vaginal microbiome (VM), the internal and external factors that influence its composition, and how it relates to adult and adolescent reproductive health.
methodsA literature review was conducted in March 2024 using Web of Science, PubMed, Embase, and Google Scholar.
resultsThe majority of studies focused on the VM in healthy adult women and demonstrated that the VM changes across the menstrual cycle, with the greatest species diversity during menses. In most women, the VM is dominated by lactobacilli, however, Black and Hispanic women are more likely to demonstrate a polymicrobial profile. The VM is also affected by lifestyle factors (e.g., diet, alcohol, smoking, sexual activity, vaginal hygiene) and contraception, whereas the role of endogenous reproductive hormones in shaping the VM is unclear. The VM of adolescents begins to resemble that of adults in mid- to late puberty.
conclusionThe VM is a complex and dynamic microbial community that has the potential to serve as an important clinical biomarker of adult as well as adolescent reproductive health, possibly aiding in the diagnosis of such conditions as polycystic ovarian syndrome. However, additional studies are needed in healthy adolescent girls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.