ArticleScience (New York, N.Y.)2024
Neanderthal ancestry through time: Insights from genomes of ancient and present-day humans.
Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Insights into Neanderthal development, childbirth, and locomotion from the Palomas and Dederiyeh pelves.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Archaic ancestry inference in imputed ancient human genomes.Nature communications · 2026Article
- Review
- Limited Selection on Neanderthal DNA in 30,780 Recently Admixed Genomes with African-like Ancestry.Molecular biology and evolution · 2026Article
- Article
- Regulation of NAT1 activity in modern humans by a novel phosphorylation site.Science advances · 2026Article
- Enhancement of hidden Markov model analyses for improved inference of archaic introgression in modern humans.Molecular biology and evolution · 2026Article
- Insights into human adaptation from ancient DNA.Nature genetics · 2026Review
- Archaic Introgression Shapes Genetic Variation at Loci Associated With DNA Virus Load in Modern Humans.Genome biology and evolution · 2026Article
- Article
- Inferring hominin history with recurrent gene flow from single unphased genomes and a two-locus statistic.bioRxiv : the preprint server for biology · 2026Article
- Recovering signatures of archaic introgression using ancestral recombination graphs.bioRxiv : the preprint server for biology · 2026Article
- Comparing Neanderthal Introgression Maps Reveals Core Agreement But Substantial Heterogeneity.Molecular biology and evolution · 2026Article
- Lithic Miniaturization Provides a Signature of an MIS4-3 Southern Dispersal of Homo sapiens.Evolutionary anthropology · 2026Review
- Interbreeding between Neanderthals and modern humans was strongly sex biased.Science (New York, N.Y.) · 2026Article
- Introgressed mitochondrial fragments from archaic hominins alter nuclear genome function in modern humans.Science advances · 2026Article
- Recent advances in methods to characterize archaic introgression in modern humans.Genome research · 2026Review
- Admixture in a butterfly species complex creates a genomic mosaic of ancestry with distinct histories for different chromosomes.bioRxiv : the preprint server for biology · 2025Article
- Genomic evidence supports the "long chronology" for the peopling of Sahul.Science advances · 2025Article
- Association of Chromosome 3p21.32 Haplotype Blocks Introgressed from Neanderthals with Critical COVID-19 in a Spanish Cohort.Life (Basel, Switzerland) · 2025Article
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7 authors.
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Abstract
Gene flow from Neanderthals has shaped genetic and phenotypic variation in modern humans. We generated a catalog of Neanderthal ancestry segments in more than 300 genomes spanning the past 50,000 years. We examined how Neanderthal ancestry is shared among individuals over time. Our analysis revealed that the vast majority of Neanderthal gene flow is attributable to a single, shared extended period of gene flow that occurred between 50,500 to 43,500 years ago, as evidenced by ancestry correlation, colocalization of Neanderthal segments across individuals, and divergence from the sequenced Neanderthals. Most natural selection-positive and negative-on Neanderthal variants occurred rapidly after the gene flow. Our findings provide new insights into how contact with Neanderthals shaped modern human origins and adaptation.
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