Evidence map›Paper›PMID 39666794›Full record

ArticleScience (New York, N.Y.)2024

Diverse phage communities are maintained stably on a clonal bacterial host.

Nora C Pyenson, Asher Leeks, Odera Nweke, Joshua E Goldford, Jonas Schluter, Paul E Turner, Kevin R Foster, Alvaro Sanchez

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Phage-Based Approaches to ChronicAntibiotics (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. A minimal model of panimmunity maintenance by horizontal gene transfer in the ecological dynamics of bacteria and phages.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nora C PyensonInstitute for Systems Genetics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0003-2631-5011
Asher LeeksDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA.
Odera NwekeDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA.ORCID 0009-0004-6287-1554
Joshua E GoldfordDivision of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA, USA.ORCID 0000-0001-7315-8018
Jonas SchluterInstitute for Systems Genetics, New York University Grossman School of Medicine, New York, NY, USA.ORCID 0000-0002-6214-9367
Paul E TurnerDepartment of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA.ORCID 0000-0003-3490-7498
Kevin R FosterDepartment of Biology, University of Oxford, Oxford, UK.ORCID 0000-0003-4687-6633
Alvaro SanchezInstitute of Functional Biology and Genomics, CSIC & University of Salamanca, Salamanca, Spain.ORCID 0000-0002-2292-5608

Funding

The unleashed microbiome of cancer patients as a discovery platform for rational microbiome engineeringDP2AI164318 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SCHLUTER, JONAS · 2021 to 2025
$2.5M
European Research CouncilNIAID NIH HHS DP2 AI164318Wellcome Trust 209397
6 · The paper itself

Abstract

Bacteriophages are the most abundant and phylogenetically diverse biological entities on Earth, yet the ecological mechanisms that sustain this extraordinary diversity remain unclear. In this study, we discovered that phage diversity consistently outstripped the diversity of their bacterial hosts under simple experimental conditions. We assembled and passaged dozens of diverse phage communities on a single, nonevolving strain of

Indexed as

Biological CoevolutionColiphagesEscherichia coliPhenotype

Identifiers

PMID39666794
PMCPMC7617280

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.