Evidence map›Paper›PMID 39666757›Full record

SynthesisPLoS neglected tropical diseases2024

Cost of dengue in Colombia: A systematic review.

Alfonso J Rodríguez-Morales, Eduardo López-Medina, Iván Arboleda, Jaime A Cardona-Ospina, Jaime Castellanos, Álvaro A Faccini-Martínez, Elaine Gallagher, Riona Hanley, Pio López, Salim Mattar and 7 more

Abstract readSystematic Review
In one paragraph

Synthesis in PLoS neglected tropical diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Economic burden of dengue in Puerto Rico, 2010-2023.Infectious diseases of poverty · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Alfonso J Rodríguez-MoralesGrupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia.
Eduardo López-MedinaColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Iván ArboledaBaxalta Colombia SAS, (Takeda), Bogotá, D.C., Colombia.ORCID 0009-0009-7291-0728
Jaime A Cardona-OspinaGrupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas-Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia.
Jaime CastellanosColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Álvaro A Faccini-MartínezServicio de Infectología, Hospital Militar Central, Bogotá D.C., Colombia.
Elaine GallagherTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Riona HanleyTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Pio LópezColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Salim MattarColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Carlos Eduardo PérezColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Randee KastnerTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Humberto ReynalesCentro de Atención e Investigación Médica-CAIMED, Chía, Cundinamarca, Colombia.
Fernando RossoInfectious Diseases Service, Fundación Valle del Lili, Cali, Valle del Cauca, Colombia.
Jing ShenTakeda Pharmaceuticals International AG, Zurich, Switzerland.
Wilmer E Villamil-GómezColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.
Marcela FuquenColombian Association of Infectious Diseases (ACIN), Bogotá, D.C., Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDengue is hyperendemic in Colombia. It imposes a substantial economic burden on patients, caregivers, society, and the national health system. We intend to identify and synthesize the evidence regarding the economic burden of dengue in Colombia.

methodsA systematic review (PROSPERO CRD42021257985) of economic studies was performed. A comprehensive search was completed in PubMed, EMBASE, the Cochrane Library, the LILACS, and SciELO databases. Study selection and data extraction was made by two researchers.

results160 records were identified. Of these, 14 studies were selected for data extraction. Direct medical cost of dengue is mainly represented by hospitalization (USD 823 to 1,754). The annual aggregated cost is near to USD 159.6 million, with ambulatory care (USD 90.1 million) and fatal cases (USD 30.7 million) representing 75% of the total cost. The aggregate indirect cost (due to loss in income while sick or as a caretaker) was USD 92.8 million. Vaccination seems to reduce the economic cost of dengue.

conclusionsDengue financial burden could be challenging for low-income communities as those affected in Colombia. An integrated approach including vector control and the introduction of a vaccine for dengue has the potential to reduce the economic burden of the disease.

Indexed as

Cost of IllnessDengueColombiaHealth Care CostsHospitalizationHumans

Identifiers

PMID39666757
PMCPMC11670977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.