Evidence map›Paper›PMID 39666255›Full record

ArticleJournal of endocrinological investigation2025

Deciphering

Valentina Berti, Elsa Fasciglione, Anne Charpiot, Flavio Montanini, Miriam Pepponi, Andrea Leo, Fabrice Hubele, David Taieb, Karel Pacak, Bernard Goichot and 1 more

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Journal of endocrinological investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Genotype-dependent [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Valentina BertiNuclear Medicine Unit, Careggi University Hospital, Florence, Italy.
Elsa FasciglioneEndocrinology, Diabetology, Nutrition, Strasbourg University Hospitals, Strasbourg University, Strasbourg, France.
Anne CharpiotOtolaryngology and Maxillofacial Surgery, Strasbourg University Hospitals, Strasbourg University, Strasbourg, France.
Flavio MontaniniNuclear Medicine Unit, Careggi University Hospital, Florence, Italy.
Miriam PepponiNuclear Medicine Unit, Careggi University Hospital, Florence, Italy.
Andrea LeoExperimental and Clinical Biomedical Sciences 'Mario Serio', Florence University, Florence, Italy.
Fabrice HubeleNuclear Medicine and Molecular Imaging, ICANS, Strasbourg University Hospitals, Strasbourg University, Strasbourg, France.
David TaiebNuclear Medicine, La Timone University Hospital, CERIMED, Aix-Marseille University, Marseille, France.
Karel PacakEunice Kennedy Shriver NICHD, National Institutes of Health, Bethesda, MD, USA.
Bernard GoichotEndocrinology, Diabetology, Nutrition, Strasbourg University Hospitals, Strasbourg University, Strasbourg, France.
Alessio ImperialeNuclear Medicine and Molecular Imaging, ICANS, Strasbourg University Hospitals, Strasbourg University, Strasbourg, France. a.imperiale@icans.eu.ORCID http://orcid.org/0000-0003-2751-5146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the influence of germline succinate dehydrogenase (SDHx) pathogenic variants on 6-[

methodsForty-seven patients (20 SDH pathogenic variants carriers) harboring 55 HNPGLs were retrospectively included. HNPGLs were delineated using Nestle adaptive threshold. 128 radiomic features were extracted and harmonized to correct for batch effects. Principal Component Analysis (PCA) was performed to remove redundancy and avoid collinearity. The most representative feature of each component was tested with multivariate stepwise logistic binary regression analysis (LBRA) to identify variables predictive of genetic status.

results

conclusionThe present study pioneers the application of

Indexed as

DihydroxyphenylalanineHead and Neck NeoplasmsParagangliomaPositron Emission Tomography Computed TomographySuccinate DehydrogenaseAdultAgedFemaleHumansMaleMiddle AgedPrognosisRadiomicsRadiopharmaceuticalsRetrospective StudiesDihydroxyphenylalaninefluorodopa F 18RadiopharmaceuticalsSuccinate Dehydrogenase18F-DOPAHead and neckParagangliomaPETRadiomicsSuccinate dehydrogenase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.