Evidence map›Paper›PMID 39666181›Full record

ArticleInternational journal of clinical pharmacy2025

Barriers and facilitators to implementing polypharmacy management frameworks: a theory based qualitative exploration of key stakeholders.

S Al Bulushi, T McIntosh, H Talkhan, A Grant, D Stewart, M Al Famy, S Cunningham

Abstract read
In one paragraph

Article in International journal of clinical pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S Al BulushiMinistry of Health, Muscat, Oman.
T McIntoshSchool of Pharmacy and Life Sciences, Applied Sciences and Public Health, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7GJ, UK.
H TalkhanDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia.
A GrantSchool of Health, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7GJ, UK.
D StewartSchool of Pharmacy and Life Sciences, Applied Sciences and Public Health, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7GJ, UK.
M Al FamyMinistry of Health, Muscat, Oman.
S CunninghamSchool of Pharmacy and Life Sciences, Applied Sciences and Public Health, Robert Gordon University, Garthdee Road, Aberdeen, AB10 7GJ, UK. s.cunningham@rgu.ac.uk.ORCID http://orcid.org/0000-0001-9655-2245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInappropriate polypharmacy arises through many factors including deficiencies in prescribing processes. Most research has focused on solutions at the clinician/patient levels with less at the organisational level.

aimTo explore key stakeholder identified barriers and facilitators to implementation of an organisational level polypharmacy management framework.

methodQualitative data were collected within the Ministry of Health in Oman. Key stakeholders were purposively sampled encompassing senior representatives of pharmacy, medicine, and nursing directors; healthcare policymakers; patient safety leaders; and academic leaders. A semi-structured interview schedule was developed informed by a recent scoping review and underpinned by the Consolidated Framework for Implementation Research (CFIR). Interviews, which continued until data saturation, were audio-recorded, transcribed and analysed using the Framework Approach.

resultsThirteen key stakeholders were interviewed, with representation of each target group. Facilitators largely mapped to the CFIR domain of inner setting (i.e., aspects of stakeholder awareness, the electronic health system and national leadership), intervention characteristic (evidence gaps), characteristics of individuals (stakeholders and champions) and process (change strategy). Barriers also largely mapped to the inner setting (policy absence, communication and health professional practice) and outer setting (resource needs).

conclusionThis study has illuminated the facilitators and barriers to the implementation of an organisational level polypharmacy management framework. Further work is required to translate these themes into an actionable plan to implement the framework. Particular attention is required for aspects of the CFIR domain of inner setting (i.e., the internal context within which implementation occurs) as most barriers mapped to this domain.

Indexed as

Inappropriate PrescribingPolypharmacyStakeholder ParticipationHumansOmanQualitative ResearchImplementation scienceOrganisational changePolypharmacy managementStrategic framework

Identifiers

PMID39666181
PMCPMC11920292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.