Evidence map›Paper›PMID 39666154›Full record

ArticleArchives of dermatological research2024

The effects of Ramadan fasting on acne vulgaris: clinical, immunological, and oxidative status considerations.

Shaimaa Ismail Omar, Khaled Fawzy El-Mulla, Nermeen Eldabah, Aziza El-Busaidy

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Article in Archives of dermatological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Shaimaa Ismail OmarDepartment of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Elkhartoum Square, El Messalah, Alexandria, 21521, Egypt. shimaa.abdelhamid@alexmed.edu.eg.ORCID http://orcid.org/0000-0001-7121-5971
Khaled Fawzy El-MullaDepartment of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Elkhartoum Square, El Messalah, Alexandria, 21521, Egypt.
Nermeen EldabahDepartment of Clinical and Chemical Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.ORCID http://orcid.org/0000-0001-8357-9588
Aziza El-BusaidyDepartment of Dermatology, Venereology and Andrology, Faculty of Medicine, Alexandria University, Elkhartoum Square, El Messalah, Alexandria, 21521, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcne vulgaris, a prevalent inflammatory skin condition, is closely linked to the immune system's regulation and oxidative stress. During Ramadan, the practice of intermittent fasting-abstaining from food and drink from dawn to sunset-can impact both body and skin health, potentially influencing the pathophysiology of acne including the immune response and the oxidative status. The objective of this study was to investigate the impact of Ramadan fasting on disease severity, Th1/Th17 cytokine levels, and oxidative status in patients with acne vulgaris.

methodThe study involved 40 patients with acne vulgaris. The severity of the condition was evaluated using the Global Acne grading System (GAGS) score, body mass index (BMI) was calculated, and levels of interleukin (IL-17), interferon gamma (IFN-γ), and Malondialdehyde (MDA) were measured both before and after the fasting period.

resultsA significant reduction in GAGS score, IL-17, IFN-γ, and MDA levels was observed after Ramadan fasting compared to before Ramadan. Additionally, the percentage decrease in GAGS score showed a positive correlation with the percentage decrease in IFN-γ.

conclusionIntermittent fasting during Ramadan could potentially benefit acne vulgaris by reducing the Th1/Th17 immune response and lowering oxidative stress.

Indexed as

Acne VulgarisFastingInterleukin-17IslamOxidative StressAdolescentAdultBody Mass IndexFemaleHumansInterferon-gammaMaleMalondialdehydeSeverity of Illness IndexTh17 CellsTh1 CellsInterferon-gammaInterleukin-17MalondialdehydeAcne vulgarisImmune responseInflammationOxidative stressRamadan fasting

Identifiers

PMID39666154

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.