Evidence map›Paper›PMID 39666124›Full record

ArticleJournal of neurology2024

Survey of common deep brain stimulation programming practices by experts in Parkinson's Disease.

J E Cunningham, L Y Cabrera, A Mahajan, S Aslam, S De Jesus, R Brennan, J Jimenez-Shahed, C C Aquino, T Xie, E O Vaou and 11 more

Abstract read
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Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

J E CunninghamCollege of Human Medicine, Michigan State University, East Lansing, MI, USA.
L Y CabreraDepartment of Engineering Science and Mechanics, Center for Neural Engineering, and Rock Ethics Institute, The Pennsylvania State University, W-316 Millennium Science Complex, University Park, PA, 16802, USA. lcabrera@psu.edu.ORCID http://orcid.org/0000-0002-6220-7096
A MahajanGardner Center for Parkinson's Disease and Movement Disorders, University of Cincinnati, Cincinnati, OH, 40059, USA.
S AslamDepartment of Neurology, University of Colorado School of Medicine, Aurora, CO, USA.
S De JesusDepartment of Neurology, Pennsylvania State University-Milton S. Hershey Medical Center, Hershey, PA, USA.
R BrennanDepartment of Neurology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.
J Jimenez-ShahedDepartment of Neurology, Bonnie and Tom Strauss Movement Disorders Center, Icahn School of Medicine at Mount Sinai, New York, NY, 10019, USA.
C C AquinoDepartment of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4P1, Canada.
T XieParkinson's Disease and Movement Disorder Clinic and DBS Program, Department of Neurology, University of Chicago Medicine, Chicago, IL, 60637, USA.
E O VaouParkinson's Disease and Movement Disorders Division, Department of Neurology, UTHealth San Antonio, San Antonio, TX, 78229, USA.
N PatelDepartment of Neurological Sciences, RUSH Parkinson's Disease and Movement Disorders Clinic, RUSH University Medical Central, Chicago, IL, 60612, USA.
M SpindlerDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19107, USA.
K A MillsJohns Hopkins Parkinson's Disease and Movement Disorder Center, Johns Hopkins University School of Medicine, Baltimore, MD, 21287, USA.
L ZhangDepartment of Neurology, The PF Center of Excellence for Movement Disorders and Neurorestoration, University of California Davis School of Medicine, Sacramento, CA, 95817, USA.
J BertoniDepartment of Neurological Sciences, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
C SidiropoulosDepartment of Neurology and Ophthalmology, Michigan State University, East Lansing, MI, 48823, USA.
S MiocinovicDepartment of Neurology, Emory University School of Medicine, Atlanta, GA, 30329, USA.
B L WalterDepartment of Neurology, Center for Neurological Restoration, Neurological Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
F PanovDepartment of Neurosurgery, Mount Sinai School of Medicine, New York, NY, USA.
S E ZauberDepartment of Neurology, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
H SarvaParkinson's Disease and Movement Disorders Institute, Department of Neurology, Weill Cornell Medicine, New York, NY, 10021, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIdentify consensus and variability in deep brain stimulation (DBS) programming practices for Parkinson's disease.

backgroundDBS programming relies on the personal experience and skills of programmers. Despite consensus statements, there aren't official guidelines for DBS programming, making it likely for protocols to vary among providers.

methodsWe administered an online survey to the Functional Neurosurgery Working Group of the Parkinson's Study Group to capture those actively programming DBS patients. We performed descriptive statistics and comparisons of responses based on career stage: early (0-10 years) versus later (>10 years).

resultsBoston Scientific (n = 15/31, 48%) and Medtronic (n = 14/35, 40%) are the two DBS systems ranked as most used, with less reported frequency of Abbott devices (n = 4/32, 12.5). Traditional monopolar review ranked as the most common initial programming strategy by 23/29 (79%) respondents, regardless of the device type implanted. Monopolar omnidirectional testing was the most often used approach for contact configuration at initial programming (24/33, 73%).For treating dyskinesia, tremor, bradykinesia, rigidity, speech-related side effects, non-motor adverse effects, or swallowing-related side effects, the most likely optimization strategy selected was to modify amplitude of the active contact. When treating freezing of gait, there was a divergence between first modifying amplitude (n = 11/29, 38%) or frequency (n = 12/33, 36%).

conclusionInitial programming practices generally align with published recommendations, which can reassure less experienced clinicians in practices with near consensus and allow them to devote more time to areas with wider variety of practice. Our data also highlights aspects of DBS programming with less consensus, demonstrating the need for future evidence.

Indexed as

Deep Brain StimulationParkinson DiseaseHumansSurveys and QuestionnairesDeep brain stimulationParkinson diseaseProgramming

Identifiers

PMID39666124

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.