Evidence map›Paper›PMID 39665763›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Facile construction of distal and diversified tertiary and quaternary stereocenters.

Chong Liu, Robbie Ge, Jun Chen, Hongmei Guo, Tyler A Bartholome, Debabrata Maiti, Haibo Ge

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chong LiuDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Robbie GeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Jun ChenDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Hongmei GuoDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Tyler A BartholomeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.
Debabrata MaitiDepartment of Chemistry, Indian Institute of Technology Bombay, Mumbai 400076, India.
Haibo GeDepartment of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409.ORCID 0000-0001-6727-4602

Funding

National Science Foundation (NSF) CHE-2029932Welch Foundation (The Welch Foundation) D-2034-20230405
6 · The paper itself

Abstract

Exploration of novel chiral pharmaceutical candidates is motivation to immersive efforts among synthetic chemists. Achieving skeletal construction and chiral diversity in a highly efficient manner is a momentous goal in the chemical society. Unfortunately, current methods for chiral induction focus primarily on a specific site. Herein, we realized the asymmetric chain-walking arylation of alkenyl alcohols for the construction of multisite tertiary and quaternary stereocenters in high yields and enantioselectivity. This new operation-friendly strategy carries substantial potential for future industrialization.

Indexed as

asymmetric catalysisC = C functionalizationchain-walkingpalladium

Identifiers

PMID39665763
PMCPMC11665887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.