ArticleThe Plant cell2024
Temperature-driven changes in membrane fluidity differentially impact FILAMENTATION TEMPERATURE-SENSITIVE H2-mediated photosystem II repair.
Article in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Tropical vulnerability and temperate resilience: molecular and physiological insights into cold stress adaptation in oil palm.GM crops & food · 2026Review
- Trp521 oxidation affects FtsH2 stability and its role in PSII repair.The New phytologist · 2026Article
- Titanium Dioxide Nanoparticle-Driven Metabolic and Molecular Reprogramming in Cyanobacteria.Molecules (Basel, Switzerland) · 2026Review
- Singlet Oxygen in Plants: Mechanistic Insights into Production, Oxidative Damage, and Stress-Response Signaling.Antioxidants (Basel, Switzerland) · 2026Review
- Integrative analysis of transcriptome and chromatin accessibility reveals promoter-proximal regulation and identifies candidate ABC transporters associated with cold stress responses in maize.BMC plant biology · 2026Article
- Integrated Proteomic and Functional Analyses Reveal the Roles of Organelle-Specific Small Heat Shock Proteins (sHSPs) in Tomato Thermotolerance.Plants (Basel, Switzerland) · 2026Article
- Chloroplastic protein PORC undergoes heat-induced condensation and enhances thermotolerance in Arabidopsis.Plant physiology · 2026Article
- Lipid remodeling and phosphatidic acid signaling maintain the vigor of recalcitrant Panax notoginseng seeds under low temperature.BMC plant biology · 2026Article
- Molecular and Physiological Regulation of Premature Leaf Senescence in Rice.Plants (Basel, Switzerland) · 2026Review
- New progress in the production, oxidative damage, and scavenging mechanisms of reactive oxygen species in plants under abiotic stress.Frontiers in plant science · 2026Review
- Thermal priming enhances heat tolerance in alfalfa (Medicago sativa L.) through activation of multiple metabolic pathways.BMC plant biology · 2025Article
- Molecular Mechanisms of Cold Stress Response in Strawberry and Breeding Strategies.Current issues in molecular biology · 2025Review
- Membrane Lipid Remodeling Strategies Regulate Fluidity for Acute Temperature Adaptation in Oysters.Evolutionary applications · 2025Article
- Article
- Characterization and Early Response of the DEAD Gene Family to Heat Stress in Tomato.Plants (Basel, Switzerland) · 2025Article
- Fixing PSII: Membrane fluidity facilitates FtsH functions.The Plant cell · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The Arabidopsis (Arabidopsis thaliana) yellow variegated2 (var2) mutant, lacking functional FILAMENTATION TEMPERATURE-SENSITIVE H2 (FtsH2), an ATP-dependent zinc metalloprotease, is a powerful tool for studying the photosystem II (PSII) repair process in plants. FtsH2, forming hetero-hexamers with FtsH1, FtsH5, and FtsH8, plays an indispensable role in PSII proteostasis. Although abiotic stresses like cold and heat increase chloroplast reactive oxygen species (ROS) and PSII damage, var2 mutants behave like wild-type plants under heat stress but collapse under cold stress. Our study on transgenic var2 lines expressing FtsH2 variants, defective in either substrate extraction or proteolysis, reveals that cold stress causes an increase in membrane viscosity, demanding more substrate extraction power than proteolysis by FtsH2. Overexpression of FtsH2 lacking substrate extraction activity does not rescue the cold-sensitive phenotype, while overexpression of FtsH2 lacking protease activity does in var2, with other FtsH isomers present. This indicates that FtsH2's substrate extraction activity is indispensable under cold stress when membranes become more viscous. As temperatures rise and membrane fluidity increases, substrate extraction activity from other isomers suffices, explaining the var2 mutant's heat stress resilience. These findings underscore the direct effect of membrane fluidity on the functionality of the thylakoid FtsH complex under stress. Future research should explore how membrane fluidity impacts proteostasis, potentially uncovering strategies to modulate thermosensitivity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.