Evidence map›Paper›PMID 39665581›Full record

ArticleEndocrine research2025

The Effects of Weight Loss and Aerobic Exercise on Cortisol and Cortisol Suppression in Postmenopausal Women with Overweight and Obesity.

Alice S Ryan, Monica C Serra, Galya Bigman, Sausan Jaber

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrine research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alice S RyanVA Research Service, Department of Medicine, Division of Gerontology, Geriatrics and Palliative Medicine at the University of Maryland School of Medicine, and the Baltimore VA Medical Center Geriatric Research, Education and Clinical Center (GRECC), VA Maryland Health Care System, Baltimore, MD, USA.ORCID 0000-0003-3708-110X
Monica C SerraDivision of Geriatrics, Gerontology & Palliative Medicine and the Sam & Ann Barshop Institute for Longevity & Aging Studies, Department of Medicine, UT Health San Antonio and the San Antonio VA GRECC, San Antonio, TX, USA.
Galya BigmanBaltimore VA Medical Center Geriatric Research, Education and Clinical Center (GRECC), VA Maryland Health Care System, Baltimore, MD, USA.
Sausan JaberBaltimore VA Medical Center Geriatric Research, Education and Clinical Center (GRECC), VA Maryland Health Care System, Baltimore, MD, USA.

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
Zonulin Antibodies in Intestinal Permeabilitiy in IDDMM01RR016500 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI ONUKWUGHA, EBERECHUKWU · 2002 to 2009
$20.2M
San Antonio OAIC - Research Education Component (REC)P30AG044271 · NIA · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Adam Salmon · 2015 to 2026
$14.1M
Race, Lipoprotein Lipase and Obesity after MenopauseR01AG020116 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI GOLDBERG, ANDREW P · 2003 to 2007
$2.2M
Diet and Exercise: Race, Postmenopause and MetabolismR01AG019310 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI RYAN, ALICE S. · 2001 to 2005
$1.5M
CSRD VA IK2 CX002768NCRR NIH HHS M01 RR016500NIA NIH HHS P30 AG028747NIA NIH HHS P30 AG044271NIA NIH HHS R01 AG019310NIA NIH HHS R01 AG020116RRD VA IK6 RX003977
6 · The paper itself

Abstract

purposeThe goal of this study was to explore the complex relationship between obesity, dietary content, weight loss, and cortisol concentrations in postmenopausal women with overweight and obesity.

methodsWomen completed basal cortisol testing, a dexamethasone suppression test (DST), DXA scan, 3-hour oral glucose tolerance test (OGTT), and food records before (

resultsAt baseline, plasma cortisol concentrations decreased significantly after DST in the entire group, a 54% suppression which was associated with basal glucose. Basal glucose levels and glucose AUC from the OGTT are associated with basal cortisol levels (

conclusionAdditional research is necessary to better comprehend cortisol regulation in postmenopausal women particularly in response to effective weight reduction interventions.

Indexed as

ExerciseHydrocortisoneObesityOverweightPostmenopauseWeight LossAgedBlood GlucoseFemaleGlucose Tolerance TestHumansMiddle AgedBlood GlucoseHydrocortisoneAerobic exercisecortisolpostmenopausal womenweight loss

Identifiers

PMID39665581
PMCPMC12045736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.