ArticleJournal of the American College of Surgeons2025
Outcomes of Palliative Hemipelvectomy in Comprehensive Cancer Center Patients with Metastatic Cancer: Retrospective Study.
Article in Journal of the American College of Surgeons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundHemipelvectomy is a complex operation that is usually performed with curative intent. It is rarely performed for palliation in patients with advanced cancer, and its efficacy in achieving palliation is unknown. STUDY
designRetrospective review of 10 patients with stage IV cancer who underwent palliative hemipelvectomy at a comprehensive cancer center.
resultsMedian age of the cohort was 60 years; 7 patients were male. Five patients had previous radiotherapy to the pelvic bone. Hemipelvectomies involved 1 to 2 Enneking-Dunham pelvic zones in 6 patients and 3 to 4 zones in 4 patients. Six patients had Clavien-Dindo complication of grade 3 or higher. Median overall survival was 6.6 months. Surgical complication resulted in death in 3 patients. At their 3-month follow-up, 5 of 8 living patients had increased narcotic requirements, and 4 of 7 with data had reduced pain (1 of whom was using high-dose intravenous narcotics). No patients experienced functional improvement, and at 6 months, 4 of the 5 who had been ambulatory preoperatively were less mobile. Outcomes tended to be better among patients whose resections were less extensive or limited to zone 3 (anterior pelvis).
conclusionsPalliative-intent hemipelvectomy provided palliation in a minority of patients, did not improve function, and had high morbidity and mortality. Patients with small anterior pelvic tumor may benefit from palliative hemipelvectomy; for others, less invasive approaches should be considered whenever feasible.
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