Evidence map›Paper›PMID 39665265›Full record

ReviewCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2025

Comprehensive Overview of Retrograde-Antegrade Connection Techniques Without Externalization in Chronic Total Occlusion PCI: The Portal Techniques.

Claudiu Ungureanu, Alexandre Avran, Emmanouil S Brilakis, Kambis Mashayekhi, Khaldoon Alaswad, Pierfrancesco Agostoni, Gabriele Gasparini, Giuseppe Colletti, Mihai Cocoi, Alexandru Achim and 10 more

Abstract readReview
In one paragraph

Review in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Tip-in balloon grenadoplasty for uncrossable chronic total occlusions.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Claudiu UngureanuCardiovascular Jolimont Hospital, La Louvière, Belgium.ORCID 0000-0002-1583-5882
Alexandre AvranDepartment of Cardiovascular, Hôpital Valenciennes, Valenciennes, France.
Emmanouil S BrilakisMinneapolis Heart Institute and Minneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.ORCID 0000-0001-9416-9701
Kambis MashayekhiClinic of Internal Medicine and Cardiology, Heart Center Lahr, Lahr, Germany.
Khaldoon AlaswadEdith and Benson Ford Heart and Vascular Institute, Henry Ford Hospital, Henry Ford Health System, Wayne State University, Detroit, Michigan, USA.
Pierfrancesco AgostoniHartCentrum Ziekenhuis Aan de Stroom (ZAS) Middelheim, Antwerp, Belgium.ORCID 0000-0002-1505-9369
Gabriele GaspariniCardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.
Giuseppe CollettiCardiovascular Department, Clinique Saint Joseph, Vivalia, Arlon, Belgium.ORCID 0000-0002-6147-0925
Mihai CocoiCardiology Department, "Niculae Stancioiu" Heart Institute, Cluj-Napoca, Romania.
Alexandru AchimCardiology Department, "Niculae Stancioiu" Heart Institute, Cluj-Napoca, Romania.ORCID 0000-0002-5540-3478
Eugene B WuPrince of Wales Hospital, Chinese University Hong Kong, Hong Kong, China.
Vojtěch NovotnýKardiologické centrum Agel, Pardubice, Czech Republic.ORCID 0000-0003-3521-9945
Mihajlo KovacicInterventional Cardiology Department, County Hospital Cakovec, Cakovec, Croatia.ORCID 0000-0002-2577-9474
Sudhir RathoreFrimley Park Hospital, NHS Foundation Trust, Camberley, UK.
Alessio La MannaAOU Policlinico "G. Rodolico-San Marco", Catania, Italy.
Timothée NoterdaemeClinique MontLégia, Department of Cardiovascular, MontLégia, Liège, Belgium.
Olivier GachClinique MontLégia, Department of Cardiovascular, MontLégia, Liège, Belgium.
Nenad BozinovicUniversity Clinical Center Niš, Niš, Serbia.ORCID 0000-0003-0515-7923
Laura NovelliCardio Center, IRCCS Humanitas Research Hospital, Rozzano-Milan, Italy.ORCID 0000-0002-1547-3252
Gregor LeibundgutDepartment of Cardiology, University Hospital Basel, Basel, Switzerland.ORCID 0000-0002-0122-5397

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvancing the retrograde microcatheter (MC) into the antegrade guide catheter during retrograde chronic total occlusion (CTO) percutaneous coronary intervention (PCI) can be challenging or impossible, preventing guidewire externalization.

objectivesTo detail and evaluate all the techniques focused on wiring to achieve intubation of the distal tip of a microcatheter, balloon, or stent with an antegrade or retrograde guidewire, aiming to reduce complications by minimizing tension on fragile collaterals during externalization and enabling rapid antegrade conversion in various clinical scenarios.

methodsWe describe the two main techniques, tip-in and rendezvous, and their derivatives such a facilitated tip-in, manual MC-tip modification, tip-in the balloon, tip-in the stent, deep dive rendezvous, catch-it and antegrade microcatheter probing. We provide case studies that demonstrate the effectiveness of these techniques in complex scenarios involving extreme vessel angulation, severe calcification, fragile collaterals, and challenging retrograde MC crossing without externalization.

conclusionThe development of advanced variants along with traditional techniques to establish retrograde guidewire connection and antegrade conversion has led to the establishment of a cohesive group of methods known as portal techniques. These approaches serve as strategic advantages in retrograde CTO-PCI, providing a valuable and feasible alternative to conventional retrograde connection techniques, particularly when those techniques fail. Their ability to avoid the externalization process reduces potential damage to collateral channels and the ostium of the donor artery, potentially leading to a reduction in complication rates.

Indexed as

Cardiac CathetersCoronary OcclusionStentsAngioplasty, Balloon, CoronaryChronic DiseaseEquipment DesignHumansMiniaturizationPercutaneous Coronary InterventionTreatment Outcomeantegrade conversionantegrade microcatheter probingchronic total occlusionrendezvousretrograde approachtip‐in

Identifiers

PMID39665265
PMCPMC11694543

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.