Evidence map›Paper›PMID 39664914›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2024

Ketosis regulates K

Helena van Nieuwenhuizen, Anthony G Chesebro, Claire Polizu, Kieran Clarke, Helmut H Strey, Corey Weistuch, Lilianne R Mujica-Parodi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Brain aging shows nonlinear transitions, suggesting a midlife "critical window" for metabolic intervention.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. bioRxiv : the preprint server for biology · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Helena van NieuwenhuizenDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11790, USA.
Anthony G ChesebroAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA, 02129, USA.
Claire PolizuRenaissance School of Medicine, Stony Brook University, Stony Brook, NY, 11790, USA.
Kieran ClarkeDepartment of Physiology, Oxford University, Oxford OX1 3PT, UK.
Helmut H StreyDepartment of Biomedical Engineering, Stony Brook University, Stony Brook, NY, 11790, USA.
Corey WeistuchDepartment of Medical Physics, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
Lilianne R Mujica-ParodiDepartment of Physics and Astronomy, Stony Brook University, Stony Brook, NY, 11790, USA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008444 · NIGMS · STATE UNIVERSITY NEW YORK STONY BROOK · PI FROHMAN, MICHAEL A. · 1992 to 2024
$12.6M
NCI NIH HHS P30 CA008748NIGMS NIH HHS T32 GM008444
6 · The paper itself

Abstract

Aging is associated with impaired signaling between brain regions when measured using resting-state fMRI. This age-related destabilization and desynchronization of brain networks reverses itself when the brain switches from metabolizing glucose to ketones. Here, we probe the mechanistic basis for these effects. First, we confirmed their robustness across measurement modalities using two datasets acquired from resting-state EEG (

Indexed as

AgingKetone EsterMetabolismMultiscale ModelingSynchrony

Identifiers

PMID39664914
PMCPMC11633768

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.