Evidence map›Paper›PMID 39664913›Full record

ArticleFrontiers in nutrition2024

Investigating the clinical predictive utility of inflammatory markers and nomogram development in colorectal cancer patients with malnutrition.

Xuexing Wang, Xingxing Tang, Jinsong Xu, Rong Zhang, Jie Chu, Chunmei Chen, Chunmei Wei

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuexing Wang *Department of Oncology, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, Kunming, China.
Xingxing Tang *Department of Thoracic Surgery, The Third People's Hospital of Honghe Hani and Yi Autonomous Prefecture, Honghe, China.
Jinsong XuDepartment of Oncology, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, Kunming, China.
Rong ZhangDepartment of Geriatric Oncology, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Kunming, China.
Jie ChuDepartment of Oncology, Ziyang Central Hospital, Ziyang, China.
Chunmei ChenDepartment of Oncology, Ziyang Central Hospital, Ziyang, China.
Chunmei WeiDepartment of Oncology, Anning First People's Hospital Affiliated to Kunming University of Science and Technology, Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The aim of this study is to investigate the relationship and prognostic significance of serum neutrophil-lymphocyte ratio (NLR), systemic immune-inflammatory index (SII), platelet-lymphocyte ratio (PLR), and prognostic nutritional index (PNI) in colorectal cancer (CRC) patients with malnutrition, as well as to construct a nomogram for predicting the onset of malnutrition. Methods: The clinical data of 391 inpatients who were hospitalized from December 1, 2021 to January 31, 2023 the diagnosis of CRC were selected and divided into a malnutrition group (121 cases) and a well-nourished group (270 cases) according to whether they were malnourished or not. Focusing on comparing the differences in serum NLR, PLR, SII index, PNI index and general information between the two groups, the Binary logistics regression analysis was used to analyze the factors affecting malnutrition, and receiver operating characteristic (ROC) curves were established to assess the predictive value of serum NLR, PLR, SII index, and PNI index individually and jointly for malnutrition, and to calculate the optimal predictive thresholds. Finally a highly accurate clinical predictive nomogram was constructed. Results: Compared with the well-nourished group, the malnourished group had higher serum NLR, SII index, PLR and lower PNI index levels, with statistically significant differences ( Conclusion: Serum NLR, SII index, PLR, and PNI are significant predictive factors for the development of malnutrition in patients with CRC. These indices, whether considered individually or collectively, possess clinical relevance in forecasting malnutrition. Furthermore, the creation of an innovative nomogram prediction model offers considerable clinical utility.

Indexed as

colorectal neoplasmsmalnutritionnomogramsnutrition assessmentsystemic immune-inflammatory

Identifiers

PMID39664913
PMCPMC11632461

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.