Evidence map›Paper›PMID 39664733›Full record

ArticleClinical case reports2024

A Case of BRASH Syndrome Presenting With Refractory Hyperkalemia Requiring Intermittent Hemodialysis.

Bikash Khadka, Saroj Poudel, Kishor Khanal, Ashim Regmi, Anup Ghimire, Sharad Shrestha, Shirish Kc, Rohini Nepal, Doctors on Wheels (DOW)

Abstract read
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bikash KhadkaDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.ORCID https://orcid.org/0000-0002-4114-8285
Saroj PoudelDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.ORCID https://orcid.org/0000-0003-0879-176X
Kishor KhanalDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.
Ashim RegmiDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.
Anup GhimireDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.
Sharad ShresthaDepartment of Anaesthesiology and Critical Care Nepal Mediciti Lalitpur Nepal.
Shirish KcDepartment of Clinical Research Doctors on Wheels Kathmandu Nepal.
Rohini NepalDepartment of Clinical Research Doctors on Wheels Kathmandu Nepal.
Doctors on Wheels (DOW)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BRASH syndrome characterized by bradycardia, renal dysfunction, atrioventricular nodal blockade (AVNB), shock, and hyperkalemia presents diagnostic and management challenges due to its complex pathophysiology and varied clinical presentations. We describe a 90-year-old woman with a history of multiple comorbidities who was on beta blockers bisoprolol for heart failure, presented with shock, refractory hyperkalemia along with bradycardia that required intermittent hemodialysis. Initial management involved aggressive hyperkalemia medical therapy and fluid resuscitation, with subsequent consideration of renal replacement therapy hemodialysis following collaboration with a multidisciplinary team, including cardiology and nephrology specialists. Despite aggressive medical management for hyperkalemia, some cases of BRASH syndrome may remain challenging to treat, requiring intermittent hemodialysis highlighting the need for further research and understanding of this complex clinical entity to improve treatment outcomes.

Indexed as

atrioventricular blockadebradycardiahyperkalemiarenal failureshock

Identifiers

PMID39664733
PMCPMC11631838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.