Evidence map›Paper›PMID 39664713›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2024

Novel high-stopping power scintillators for medical applications.

J Glodo, E van Loef, Y Wang, P Bhattacharya, L Soundara Pandian, U Shirwadkar, I Hubble, J Schott, M Muller

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J GlodoRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
E van LoefRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
Y WangRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
P BhattacharyaRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
L Soundara PandianRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
U ShirwadkarRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
I HubbleRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
J SchottRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.
M MullerRadiation Monitoring Devices, Inc., 44 Hunt St., Watertown, MA, USA 02472- 4624.

Funding

TOF-PET with high-efficiency TlCl crystalsR01EB034062 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Gerard Arino Estrada · 2023 to 2026
$2.5M
High-performance and cost-effective detector modules based on ultra-dense and fast ceramic scintillator for long axial field-of-view positron emission tomographyR01EB030538 · NIBIB · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KWON, SUN IL · 2021 to 2024
$2.2M
Ultra-dense ceramic scintillator for BrainPET scannerR44MH135525 · NIMH · RADIATION MONITORING DEVICES, INC. · PI JAROSLAW GLODO · 2023 to 2026
$2.0M
Ultra-dense and Fast Ceramic Scintillator for PETR44CA243762 · NCI · RADIATION MONITORING DEVICES, INC. · PI GLODO, JAROSLAW · 2020 to 2022
$1.5M
Tl-Halide Scintillators for TOF-PETR44EB031656 · NIBIB · RADIATION MONITORING DEVICES, INC. · PI GLODO, JAROSLAW · 2021 to 2023
$1.5M
NCI NIH HHS R44 CA243762NIBIB NIH HHS R01 EB030538NIBIB NIH HHS R01 EB034062NIBIB NIH HHS R44 EB031656NIMH NIH HHS R44 MH135525
6 · The paper itself

Abstract

Development of new scintillator materials is a continuous effort, which recently has been focused on materials with higher stopping power. Higher stopping power can be achieved if the compositions include elements such as Tl (Z=81) or Lu (Z=71), as the compounds gain higher densities and effective atomic numbers. In context of medical imaging this translates into high detection efficiency (count rates), therefore, better image quality (statistics, thinner films) or lower irradiation doses to patients in addition to lowering of cost. Many known scintillator hosts, commercial or in research stages, are alkali metal halides (Cs, K, Rb). Often these monovalent ions can be replaced with monovalent Tl. Since Tl has a higher atomic number than for example Cs (55), this increases the stopping power of modified compounds. A good example of an enhanced host is Ce doped Tl

Indexed as

Lu2O3Medical ImagingPETRadiation DetectorsScintillatorsTl2LaCl5Tl2LiYCl6Tl-based compositionsTlCl

Identifiers

PMID39664713
PMCPMC11631204

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.