Evidence map›Paper›PMID 39664371›Full record

ArticleBMJ public health2024

Modifiable risk factors for dementia in India: A cross-sectional study revisiting estimates and reassessing prevention potential and priorities.

Marco Angrisani, Emma Nichols, Erik Meijer, Alden L Gross, Joshua R Ehrlich, Mathew Varghese, Kenneth M Langa, A B Dey, Sara D Adar, Jinkook Lee

Abstract read
In one paragraph

Article in BMJ public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Superficial white matter and gray matter jointly support cognition among older adults in India.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Article
  5. Article
  6. The landscape of dementia in India: Prevalence, risk factors, and opportunities ahead.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Sensory impairment and dementia risk among older adults in rural South Africa.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marco AngrisaniCenter for Economic and Social Research, University of Southern California, 635 Downey Way, Los Angeles, CA 90089, USA.
Emma NicholsCenter for Economic and Social Research, University of Southern California, 635 Downey Way, Los Angeles, CA 90089, USA.
Erik MeijerCenter for Economic and Social Research, University of Southern California, 635 Downey Way, Los Angeles, CA 90089, USA.
Alden L GrossDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, USA; Center on Aging and Health, Johns Hopkins University, 2024 E Monument St, Baltimore, MD 21205, USA.
Joshua R EhrlichUniversity of Michigan Department of Ophthalmology and Visual Sciences, 1000 Wall St, Ann Arbor, MI 48105, USA.
Mathew VargheseDepartment of Psychiatry, St. John's Medical College, Sarjapur Main Rd, John Nagar, Koramangala, Bengaluru, Karnataka 560034, India.
Kenneth M LangaUniversity of Michigan Institute for Social Research, 426 Thompson St, Ann Arbor, MI 48104, USA.
A B DeyVenu Geriatric Institute, Sheikh Sarai Institutional Area-II, New Delhi, 110 017, India.
Sara D AdarUniversity of Michigan School of Public Health, 1415 Washington Heights, Ann Arbor, MI 48109, USA.
Jinkook LeeCenter for Economic and Social Research, University of Southern California, 635 Downey Way, Los Angeles, CA 90089, USA.

Funding

Leveraging a natural experiment to estimate the causal impact of blood sugar on dementia and cognition in IndiaR01AG051125 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Jinkook Lee · 2015 to 2026
$26.8M
Health and Retirement Study: Harmonized Cognitive Assessment Protocol (HCAP)U01AG058499 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LANGA, KENNETH M · 2018 to 2023
$8.3M
Modifiable Protective and Risk Factors of Late-Life Cognitive Health and DementiaRF1AG055273 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LANGA, KENNETH M, LEE, JINKOOK · 2017 to 2017
$4.0M
NIA NIH HHS R01 AG051125NIA NIH HHS RF1 AG055273NIA NIH HHS U01 AG058499
6 · The paper itself

Abstract

Background: About 16% of worldwide dementia cases are in India. Evaluating the prospects for dementia prevention in India requires knowledge of context-specific risk factors, as relationships between risk factors and dementia observed in high-income countries (HICs) may not apply. Methods: We computed population attributable fractions (PAFs) for dementia in India by estimating associations between risk factors and dementia, their prevalence and communality, within the same nationally representative sample of 4,096 Indians aged 60 and older, surveyed through the Harmonized Diagnostic Assessment of Dementia for the Longitudinal Aging Study in India (LASI-DAD). Results: The risk factor with the largest PAF (>20%) was no education, followed by vision impairment (14%), physical inactivity (12%), and social isolation (8%). According to our estimates, eliminating exposure to risk factors significantly associated with dementia would potentially prevent up to 70% of dementia cases in India. Discussion: Previous estimates, based on samples limited to specific geographic areas and using risk factors' definitions and relative risks from HICs, may not correctly estimate the real opportunities for preventing dementia in India or identify the most critical areas for intervention.

Indexed as

Alzheimer’s disease and related dementiadementia risk factorsIndiapopulation attributable fractions

Identifiers

PMID39664371
PMCPMC11633656

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.