ArticleFrontiers in oncology2024
Dosimetric scorecards express precise clinical intent: alternate hippocampal-sparing whole-brain RapidPlan models favoring target coverage and homogeneity at 30 and 20 Gy.
Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Beam geometry optimization and convergence mode evaluation for knowledge-based planning of hippocampal avoidance whole-brain radiotherapy: A cross-platform study with quantitative scorecard assessment.Journal of applied clinical medical physics · 2026Article
- A Comprehensive Dosimetric and Plan Quality Evaluation of Non-coplanar VMAT With Flattening Filter-free Versus Flattened Beams for Hippocampal-Avoidance Whole-Brain Radiotherapy: A Multi-Platform Study on Elekta Infinity and UIH uRT-Linac Systems.Technology in cancer research & treatmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: This study develops two new multi-institutional hippocampal-sparing whole-brain RapidPlan™ models (HLS-EC-WB and HMS-EC-WB) inspired by CCTG-CE.7 featuring enhanced target coverage with varying hippocampal sparing (limited and moderate). Methods: New dosimetric scorecards were created to quantify the models' clinical intent. The models were trained using a multi-institution dataset, and a recursive method was employed to generate consistent, high-quality plans. The models were validated using a five-case set and compared at 20- and 30-Gy prescriptions. Results: Each model scored highest on its associated dosimetric scorecard. The new models achieved higher brain PTV prescription coverage (98%-99%) compared to the previous HSWBv2 model (95.12%), with some trade-off in hippocampal sparing. Conclusions: Three high-quality automated RapidPlan™ models for hippocampal-sparing whole brain are now available, each with a distinct dosimetric scorecard. The new models prioritize increased PTV coverage at some expense to hippocampal sparing. All models, example plans, scorecards, and scoring tools are freely available online.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.