Evidence map›Paper›PMID 39664177›Full record

ArticleFrontiers in oncology2024

Derivation of a comprehensive semi-empirical proton RBE model from published experimental cell survival data collected in the PIDE database.

Jian-Yue Jin, Jiankui Yuan, Xiaohang Qin, Yinghui Li, Huagang Yan, Nancy L Oleinick, Min Yao, Quintin Pan, Feng-Ming Spring Kong, Mitchell Machtay

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Article in Frontiers in oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jian-Yue JinSchool of Biomedical Engineering, Capital Medical University, Beijing, China.
Jiankui YuanSeidman Cancer Center, University Hospitals, Cleveland Medical Center, Cleveland, OH, United States.
Xiaohang QinSchool of Biomedical Engineering, Capital Medical University, Beijing, China.
Yinghui LiSchool of Biomedical Engineering, Capital Medical University, Beijing, China.
Huagang YanSchool of Biomedical Engineering, Capital Medical University, Beijing, China.
Nancy L OleinickCase Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States.
Min YaoDepartment of Radiation Oncology, Penn State University Cancer Institute, Hershey, PA, United States.
Quintin PanSeidman Cancer Center, University Hospitals, Cleveland Medical Center, Cleveland, OH, United States.
Feng-Ming Spring KongDepartment of Clinical Oncology, Hong Kong University Shenzhen Hospital, Shenzhen, China.
Mitchell MachtayDepartment of Radiation Oncology, Penn State University Cancer Institute, Hershey, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aimed to develop a comprehensive proton relative biological effectiveness (RBE) model based on accumulated cell survival data in the literature. Our approach includes four major components: (1) Eligible cell survival data with various linear energy transfers (LETs) in the Particle Irradiation Data Ensemble (PIDE) database (72 datasets in four cell lines); (2) a cell survival model based on Poisson equation, with

Indexed as

cell survival modellinear energy transfer (LET)multiple curve fitting (MCF)proton therapyrelative biological effectiveness (RBE)

Identifiers

PMID39664177
PMCPMC11631728

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.