Evidence map›Paper›PMID 39663954›Full record

ArticleFood & function2025

A pilot study of metaproteomics and DNA metabarcoding as tools to assess dietary intake in humans.

Brianna L Petrone, Alexandria Bartlett, Sharon Jiang, Abigail Korenek, Simina Vintila, Christine Tenekjian, William S Yancy, Lawrence A David, Manuel Kleiner

Abstract read
In one paragraph

Article in Food & function, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Sequencing what we eat.Nature reviews. Gastroenterology & hepatology · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Brianna L PetroneDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. lawrence.david@duke.edu.ORCID http://orcid.org/0000-0003-4778-7595
Alexandria BartlettDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. lawrence.david@duke.edu.
Sharon JiangDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. lawrence.david@duke.edu.
Abigail KorenekDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA. manuel_kleiner@ncsu.edu.
Simina VintilaDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA. manuel_kleiner@ncsu.edu.
Christine TenekjianDuke Lifestyle and Weight Management Center, Durham, NC, USA.
William S YancyDuke Lifestyle and Weight Management Center, Durham, NC, USA.
Lawrence A DavidDepartment of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. lawrence.david@duke.edu.
Manuel KleinerDepartment of Plant and Microbial Biology, North Carolina State University, Raleigh, NC, USA. manuel_kleiner@ncsu.edu.ORCID http://orcid.org/0000-0001-6904-0287

Funding

Medical Scientist Training Program Training GrantT32GM145449 · NIGMS · DUKE UNIVERSITY · PI Christopher D Kontos · 2022 to 2026
$6.6M
Personalizing prebiotic therapies that target human gut microbiotaR01DK116187 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2018 to 2026
$3.7M
Using DNA sequencing to assess dietary species richnessR01DK128611 · NIDDK · DUKE UNIVERSITY · PI Lawrence Anthony David · 2022 to 2026
$2.9M
Metaproteomics to investigate intestinal microbiota-host and -diet interactionsR35GM138362 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KLEINER, MANUEL · 2020 to 2024
$1.9M
NIDDK NIH HHS R01 DK116187NIDDK NIH HHS R01 DK128611NIGMS NIH HHS R35 GM138362NIGMS NIH HHS T32 GM145449
6 · The paper itself

Abstract

Objective biomarkers of food intake are a sought-after goal in nutrition research. Most biomarker development to date has focused on metabolites detected in blood, urine, skin, or hair, but detection of consumed foods in stool has also been shown to be possible

Indexed as

DNA Barcoding, TaxonomicFecesProteomicsAdultBiomarkersDietDNAFemaleHumansMaleMiddle AgedPilot ProjectsBiomarkersDNA

Identifiers

PMID39663954
PMCPMC11635405

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.