Evidence map›Paper›PMID 39663754›Full record

ArticleBJPsych open2024

A proof-of-concept analysis of data from the first NHS clinic for young adults with comorbid cannabis use and psychotic disorders.

Marta Di Forti, Benjamin W Bond, Edoardo Spinazzola, Giulia Trotta, Jodie Lynn, Richard Malkin, Naba Kamran Siddiqui, Sultan Demir, Titilayomi Opadokun, Perry B M Leung and 13 more

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BJPsych open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07245212 (Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07245212 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Testing the Efficacy of the Cannabis Clinic for Patients With Psychosis (CCP) Intervention for Cannabis Use Reduction/Cessation in Patients With First Episode Psychosis

TypeinterventionalSponsorKing's College LondonRan2025 to 2028Enrolled80ConditionsPsychosis, Cannabis Use Disorder, First Episode Psychosis (FEP)ArmsCCP Intervention
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. An etiological approach to psychosis: potential benefits for treatment, research and prevention.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  2. Child and adolescent psychiatry: challenges, solutions, opportunities, and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Marta Di FortiDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.ORCID https://orcid.org/0000-0002-3218-6925
Benjamin W BondSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Edoardo SpinazzolaSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Giulia TrottaDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Jodie LynnSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Richard MalkinSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Naba Kamran SiddiquiSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Sultan DemirSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Titilayomi OpadokunSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Perry B M LeungDepartment of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.ORCID https://orcid.org/0000-0002-5292-5641
Zhikun LiDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Andrea QuattroneSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Gabriella BaxterSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Elizabeth Appiah-KusiSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Tom P FreemanAddiction and Mental Health Group University of Bath, UK.
Hannah WalshDepartment of Addictions, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Tommaso SqueriGKT School of Medical Education, King's College London, UK.ORCID https://orcid.org/0000-0002-5123-1429
Daria SemikinaSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Felicity Amberson-JonesSouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.
Isabelle Austin-ZimmermanDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Tim MeynenDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Diego QuattroneDepartment of Social Genetics and Developmental Psychiatry, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
Robin M MurraySouth London and Maudsley NHS Foundation Mental Health Trust, London, UK.

Funding

Maudsley Charity 2485Maudsley Charity 2863Medical Research Council MR/T007818/1
6 · The paper itself

Abstract

backgroundCannabis use severely affects the outcome of people with psychotic disorders, yet there is a lack of treatments. To address this, in 2019 the National Health Service (NHS) Cannabis Clinic for Psychosis (CCP) was developed to support adults suffering from psychosis to reduce and/or stop their cannabis use.

aimsExamine outcome data from the first 46 individuals to complete the CCP's intervention.

methodThe sample (

resultsA reduction in the mean CUDIT-R score was observed between T0 (mean difference = 17.10, 95% CI = 15.54-18.67) and T1, with 73.91% of participants achieving abstinence and 26.09% reducing the frequency and potency of their use. Significant improvements in all clinical and functional outcomes were observed, with 90.70% being in work or education at T1 compared with 8.70% at T0. The variance in CUDIT-R scores explained between 34 and 64% of the variance in our secondary measures.

conclusionsThe CCP intervention is a feasible strategy to support cannabis use cessation/reduction and improve clinical and functional outcomes of people with psychotic disorders.

Indexed as

Cannabis usecessationpersonalisedpsychosispsychosocial interventions

Identifiers

PMID39663754
PMCPMC11733490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.