Evidence map›Paper›PMID 39663614›Full record

SynthesisJournal of Korean Academy of Nursing2024

Exploring Symptom Cluster Patterns in Adult Cancer Patients Undergoing Chemotherapy: A Systematic Review.

Pan Yang, Hui-Juan Mei, Hao-Yu Zhao, Rong-Rong Wu, Yong-Qin Ge, Yin Lu

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of Korean Academy of Nursing, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Gastrointestinal symptom profiles after resection of esophageal or gastric cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pan Yang *Department of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0000-0002-7224-4157
Hui-Juan Mei *Department of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0009-0002-7950-9581
Hao-Yu ZhaoDepartment of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0009-0001-4028-5835
Rong-Rong WuDepartment of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China.ORCID https://orcid.org/0009-0001-0838-9722
Yong-Qin GeDepartment of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China. geyongqin@suda.edu.cn.ORCID https://orcid.org/0009-0002-8951-1634
Yin LuDepartment of Hematology, First Affiliated Hospital of Soochow University, Suzhou, China. luyin@suda.edu.cn.ORCID https://orcid.org/0009-0008-3327-9788

Funding

Science and Technology Project of Suzhou SKJY2021064
6 · The paper itself

Abstract

purposeThis systematic review aimed to scrutinize the progression of symptom cluster research in adult cancer patients who received primary or adjuvant chemotherapy between 2001 and 2023, providing a comprehensive understanding of clinical practice and future research.

methodsPubMed, Ovid MEDLINE, Excerpta Medica Database, Cumulative Index to Nursing and Allied Health Literature, Cochrane Library, and Web of Science databases were searched for theme words and free words related to symptom clusters, cancer, and chemotherapy. Eligible studies were published between January 1, 2001, and May 30, 2023; adults who were diagnosed with cancer and received primary or adjuvant chemotherapy were evaluated.

resultsTwenty-nine studies were included in this review. The Memorial Symptom Assessment Scale emerged as the predominant instrument and exploratory factor analysis was the most frequently employed statistical method to identify symptom clusters. Psychological, gastrointestinal, and physical image symptom clusters were the most commonly delineated. Furthermore, the temporal stability of the symptom clusters showed varying dynamics, with psychological symptom clusters displaying relative consistency over time.

conclusionInterventions are needed for the most common and stable symptoms in patients with cancer undergoing chemotherapy. Future endeavors may necessitate more longitudinal studies to delve deeper into the temporal stability and dynamic variations of symptom clusters. Such investigations hold promise for advancing symptom cluster research, elucidating the underlying mechanisms, and fostering the development of targeted interventions, thereby enriching the symptom management paradigm in oncological care.

Indexed as

NeoplasmsAdultAntineoplastic AgentsDatabases, FactualHumansAntineoplastic AgentsCancerChemotherapySymptom Cluster

Identifiers

PMID39663614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.