Evidence map›Paper›PMID 39663529›Full record

ArticleNeurological research and practice2024

Psychological interventions for improvement of symptoms of post-stroke depression - study protocol of the depression-intervention study for optimization of reconvalesence after stroke (DISCOVER).

Lino Braadt, Simone Fischer, Markus Naumann, Philipp Zickler, Thomas Schneider-Axmann, Laura Mühlich, Katharina Körber, Alexander Lassner, Wolfgang Strube, Astrid Röh and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurological research and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lino BraadtNeurology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany. Lino-Dominic.Braadt@uk-augsburg.de.ORCID http://orcid.org/0009-0005-9896-4274
Simone FischerEpidemiology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.
Markus NaumannNeurology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.
Philipp ZicklerNeurology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.
Thomas Schneider-AxmannDepartment of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany.
Laura MühlichDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Katharina KörberDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Alexander LassnerDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Wolfgang StrubeDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Astrid RöhDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Alkomiet HasanDepartment of Psychiatry, Psychotherapy and Psychosomatics, Faculty of Medicine, University of Augsburg, Geschwister-Schönert-Str. 1, 86156, Augsburg, Germany.
Michael ErtlNeurology, Faculty of Medicine, University of Augsburg, Stenglinstrasse 2, 86156, Augsburg, Germany.

Funding

Bayerisches Staatsministerium für Gesundheit, Pflege und Prävention Bayerisches Staatsministerium für Gesundheit, Pflege und Prävention
6 · The paper itself

Abstract

introductionBesides functional outcomes, mental health and health-related quality of life (HRQoL) are significant measures in chronic diseases, such as stroke. Post-stroke depression (PSD) is an important complication affecting up to one in three stroke survivors. So far, specific programs to screen, detect and treat these patients are lacking but might be a crucial component in stroke aftercare.

methodsBetween March 2024 and Febuary 2025 all consecutive adult patients with stroke, admitted to the University Hospital of Augsburg, are screened for signs of depression (PHQ-9 (Patient Health Questionnaire-9) score of ≥ 10). Eight weeks later, those patients with persisting signs of depression will be randomized to receive either a behavioural activation intervention or a mindfulness-based intervention via telephone. Depressive symptoms will be assessed at baseline (V1), after 84, 180 (V2-V3) and after 365 days (V4) using the PHQ-9 score. Secondary outcomes include the functional outcome, quality of life (EuroQol-5 Dimensions; EQ-5D), overall functioning, and incidence of major cardiovascular events including recurrent transient ischemic attack, stroke, and mortality. PERSPECTIVE: Our aim is to provide proof-of-concept evidence for the efficacy of telepsychological need-adapted interventions for patients with post-stroke depression. Regular screening for PSD with implementation of a feasible treatment option could reduce the long-term prevalence of PSD and improve quality of life.

trial registrationThis trial was registered at German Clinical Trials Register (DRKS) on 07.03.2024, ID: DRKS00033792. German Clinical Trials Register (drks.de).

Indexed as

Post-stroke depressionRehabilitationStrokeTelepsychological intervention

Identifiers

PMID39663529
PMCPMC11633058

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.