Evidence map›Paper›PMID 39663512›Full record

Trial reportBMC pulmonary medicine2024

Physiologic effects of prone positioning on gas exchange and ventilation-perfusion matching in awake patients with AHRF.

Yali Chao, Xueyan Yuan, Zhanqi Zhao, Inéz Frerichs, Zhe Li, Qin Sun, Dongyu Chen, Rui Zhang, Haibo Qiu, Ling Liu

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04754113 (Effect of Prone Position on Lung Ventilation and Perfusion Matching in Non-intubated Patients With COVID-19 Pneumonia), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04754113 nacompletednot on this map

Effect of Prone Position on Lung Ventilation and Perfusion Matching in Non-intubated Patients With COVID-19 Pneumonia

TypeinterventionalSponsorSoutheast University, ChinaRan2021 to 2022Enrolled14ConditionsCovid19Armsprone position
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Prone positioning in ARDS.Intensive care medicine · 2026
    Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yali Chao *Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Xueyan Yuan *Jiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Zhanqi ZhaoInstitute of Technical Medicine, Furtwangen University, Villingen-Schwenningen, Germany.
Inéz FrerichsDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center of Schleswig-Holstein Campus, Kiel, Germany.
Zhe LiDepartment of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Qin SunJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Dongyu ChenJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Rui ZhangJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Haibo QiuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China.
Ling LiuJiangsu Provincial Key Laboratory of Critical Care Medicine, Department of Critical Care Medicine, School of Medicine, Zhongda Hospital, Southeast University, Nanjing, Jiangsu, 210009, China. liulingdoctor@126.com.

Funding

Jiangsu Provincial Key Laboratory of Critical Care Medicine BM2020004National Natural Science Foundation of China 82341032, and 81930058National Science and Technology Major Project of China 2022YFC2504400the Second Level Talents of the "333 High Level Talents Training Project" in the sixth phase in Jiangsu LGY2022025
6 · The paper itself

Abstract

backgroundProne positioning (PP) improves oxygenation in awake patients with acute hypoxemic respiratory failure (AHRF). However, the underlying mechanisms remain unclear in patients with diverse lung morphology. We aimed to determine the short-term effects of awake prone positioning (APP) in AHRF patients with focal and non-focal lung morphology.

methodsThis is a prospective physiological study. Twenty-four non-intubated patients with PaO

resultsTwelve of the included patients were classified to the focal group and 12 to the non-focal group. PaO

conclusionsAPP improves V/Q matching, and large-scale, bias-free studies are needed to find more definitive differences between patients with focal and non-focal lung morphyology.

trial registrationThe study is registered in ClinicalTrials.gov (trial No. NCT04754113, date of registration: 2021-02-15).

Indexed as

Pulmonary Gas ExchangeRespiratory InsufficiencyAgedFemaleHemodynamicsHumansHypoxiaLungMaleMiddle AgedPatient PositioningProne PositionProspective StudiesTomography, X-Ray ComputedVentilation-Perfusion RatioWakefulnessAcute hypoxemic respiratory failureAwake prone positioningDead spaceShuntVentilation-perfusion matching

Identifiers

PMID39663512
PMCPMC11633027

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.