Evidence map›Paper›PMID 39662917›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Efficacy of the Bridge Dry Swallowing Exercise for Refractory Gastroesophageal Reflux Disease.

Tomoko Nishimura, Kenjiro Kunieda, Kei Aoyama, Takahito Shimomura, Toshio Suzuki, Yoshikazu Inagaki, Naomi Ban, Hideki Nakamura, Kyoko Sakamoto, Kenji Itani and 5 more

Abstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Tomoko NishimuraDepartment of Gastroenterology, Nishijin Hospital, Japan.
Kenjiro KuniedaDepartment of Neurology, Gifu University Graduate School of Medicine, Japan.
Kei AoyamaDepartment of Rehabilitation Medicine, Chikamori Rehabilitation Hospital, Japan.
Takahito ShimomuraDepartment of Gastroenterology, Nishijin Hospital, Japan.
Toshio SuzukiDepartment of Gastroenterology, Nishijin Hospital, Japan.
Yoshikazu InagakiDepartment of Gastroenterology, Nishijin Hospital, Japan.
Naomi BanDepartment of Gastroenterology, Nishijin Hospital, Japan.
Hideki NakamuraDepartment of Gastroenterology, Nishijin Hospital, Japan.
Kyoko SakamotoDepartment of Gastroenterology, Nishijin Hospital, Japan.
Kenji ItaniDepartment of Gastroenterology, Nishijin Hospital, Japan.
Takefumi NishimuraDepartment of Rehabilitation Technique, Nishijin Hospital, Japan.
Fumiya NakamuraDepartment of Rehabilitation Technique, Nishijin Hospital, Japan.
Kyoichi KassaiDepartment of Gastroenterology, Nishijin Hospital, Japan.
Tomohisa OhnoDepartment of Dentistry, Hamamatsu City Rehabilitation Hospital, Japan.
Ichiro FujishimaDepartment of Rehabilitation Medicine, Hamamatsu City Rehabilitation Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Gastroesophageal reflux disease (GERD) is a condition characterized by reflux of gastric contents, leading to damage to the esophageal mucosa and/or unpleasant symptoms, with a global prevalence of 13%. Although acid-suppressive medications are currently the most effective treatments for GERD, they may be ineffective against its symptoms. We therefore investigated the efficacy of a physical exercise program for the treatment of intractable GERD symptoms. Methods Fifteen participants who underwent upper gastrointestinal endoscopy were included in this study. They received acid-suppressive drugs for more than eight weeks and had a score of ≥8 on the Frequency Scale for the Symptoms of GERD (FSSG). Participants were instructed to perform a 2-week interventional exercise program comprising drinking saliva 10 times in the bridge position (bridge dry swallowing exercise). This involved swallowing saliva without any food or drink while the hip was raised in the supine position. Changes in the FSSG scores after exercise were examined (UMIN000047829). Results Among the 15 participants, 7 were men, with a median age of 59 years old. Each participant had mild reflux esophagitis or no mucosal injuries. All participants completed the exercise program safely. Of the 15 participants, 13 demonstrated an improvement in the FSSG score after the intervention. The total FSSG score improved significantly from a median of 17 to 11 (p <0.001). Five participants discontinued acid-suppressive drugs after the intervention ended. Conclusions Bridge dry swallowing exercises can improve the intractable symptoms of GERD. However, further studies are required to verify its efficacy and safety.

Indexed as

DeglutitionExercise TherapyGastroesophageal RefluxAdultAgedFemaleHumansMaleMiddle AgedSalivaTreatment Outcomeesophageal rehabilitationgastroesophageal reflux diseaselower esophageal sphincterproton pump inhibitorsrefractory gastroesophageal reflux disease

Identifiers

PMID39662917
PMCPMC12241778

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.