Evidence map›Paper›PMID 39662914›Full record

ArticleInternal medicine (Tokyo, Japan)2025

The Association between Sarcopenia and Constipation Onset in Community-dwelling Older Adults in Japan.

Hiroaki Nakagawa, Taro Takeshima, Akihiro Ozaka, Sho Sasaki, Sugihiro Hamaguchi, Shunichi Fukuhara

Abstract read
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiroaki NakagawaCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.
Taro TakeshimaCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.
Akihiro OzakaCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.
Sho SasakiCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.
Sugihiro HamaguchiCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.
Shunichi FukuharaCenter for Innovative Research for Communities and Clinical Excellence (CiRC²LE), Fukushima Medical University Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective Constipation is an important symptom in older adults. Sarcopenia is associated with constipation, but its directionality remains unclear. The present study assessed the association between sarcopenia and new-onset constipation. Methods This prospective cohort study assessed sarcopenia at baseline in 2019 using the the Strength, Assistance with walking, Rising from a chair, Climbing stairs, and Falls (SARC-F) questionnaire. Sarcopenia was defined as a SARC-F score of ≥4. Constipation was measured in 2019 and 2020 based on self-reported constipation or laxative use, using a self-administered questionnaire. Logistic regression was used to estimate the association between new-onset constipation in 2020 and sarcopenia status at the baseline. Patients Independent community-dwelling adults ≥75 years old in Sukagawa City, Fukushima, Japan. Results The analysis included 2,388 participants without constipation at baseline (mean age: 80.0±4.3 years old; 44.9% men), of whom 310 (13.0%) had sarcopenia at baseline. Overall, 262 participants (11.0%) developed constipation, including 57 of 310 (18.4%) with sarcopenia and 205 of 2,078 (9.9%) without sarcopenia. Participants with sarcopenia had a significantly higher risk of developing constipation than those without sarcopenia after adjusting for age, sex, lifestyle factors, and comorbidities (adjusted odds ratio, 1.98; 95% confidence interval, 1.40-2.81; p<0.001). The association between sarcopenia and new-onset constipation remained statistically significant at higher and lower SARC-F cutoff values. Conclusion Sarcopenia was associated with new-onset constipation. Sarcopenia is a risk factor for constipation in independent community-dwelling older adults ≥75 years old. Measures addressing sarcopenia may help prevent constipation in older adults.

Indexed as

ConstipationIndependent LivingSarcopeniaAgedAged, 80 and overFemaleHumansJapanMaleProspective StudiesRisk FactorsSurveys and Questionnairesconstipationolder adultsprimary health careprospective cohort studysarcopenia

Identifiers

PMID39662914
PMCPMC12287569

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.