Evidence map›Paper›PMID 39662713›Full record

ArticleJournal of the American College of Radiology : JACR2025

Impact of a Clinical Decision Support System on CT Pulmonary Angiography Yield and Utilization in Hospitalized Patients.

Amita Sharma, Mark Isabelle, Andetta Hunsaker, Sayon Dutta, David Lucier, Rachel P Rosovsky, Sanjay Saini, Adam Landman, Ali S Raja, Ramin Khorasani and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American College of Radiology : JACR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amita SharmaMedical Director of CT, Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Mark IsabelleCenter for Evidence-Based Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts.
Andetta HunsakerHarvard Medical School, Boston, Massachusetts; Chief, Division of Thoracic Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, Massachusetts.
Sayon DuttaHarvard Medical School, Boston, Massachusetts; Physician Lead for Emergency Medicine and Clinical Decision Support at Partners eCare, Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts.
David LucierHarvard Medical School, Boston, Massachusetts; Associate Chief Quality Officer and Vice President of Hospital Quality, Division of General Internal Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Rachel P RosovskyHarvard Medical School, Boston, Massachusetts; Director, Thrombosis Research, Co-Chair, Thrombosis Committee, and Co-Chair, Thrombosis and Hemostasis Management Quality Collaborative, Division of Hematology/Oncology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Sanjay SainiHarvard Medical School, Boston, Massachusetts; Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts; Vice Chairman for Finance, Massachusetts General Hospital Imaging, Boston, Massachusetts.
Adam LandmanHarvard Medical School, Boston, Massachusetts; Chief Information Officer and Senior Vice President, Digital, Mass General Brigham, Boston, Massachusetts.
Ali S RajaHarvard Medical School, Boston, Massachusetts; Center for Evidence-Based Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; Deputy Chair, Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Ramin KhorasaniHarvard Medical School, Boston, Massachusetts; Center for Evidence-Based Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts; Vice Chair, Radiology Quality and Safety, Mass General Brigham, Boston, Massachusetts; Vice Chair of Radiology and Director of Center for Evidence-Based Imaging, Brigham and Women's Hospital, Boston, Massachusetts.
Ronilda LacsonHarvard Medical School, Boston, Massachusetts; Associate Director, Center for Evidence-Based Imaging, Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts. Electronic address: rlacson@bwh.harvard.edu.

Funding

AHRQ HHS R18 HS028616
6 · The paper itself

Abstract

purposeThe aims of this study were to determine whether point-of-order clinical decision support (CDS) based on the Wells criteria improves CT pulmonary angiography (CTPA) yield and utilization in hospitalized patients in an enterprise-wide health system and to identify yield-related factors.

methodsThis retrospective, institutional review board-approved, cross-sectional study in an urban, multi-institution health system included hospitalized patients undergoing CTPA 12 months before and after CDS implementation (entire cohort). The χ

resultsFor 2,429 inpatient CT pulmonary angiographic examinations after the intervention, CTPA yield was significantly higher when CDS recommendations were followed (18.3% [250 of 1,365]) compared with those overridden (14.2% [151 of 1,064]) (P < .01). For 5,372 CT pulmonary angiographic examinations in the entire cohort, there was no difference in PE yield before (448 of 2,943 [15.2%]) versus after (401 of 2,429 [16.5%]) CDS implementation (P = .20). However, in 340,146 admissions over the study period, a 7.4% relative decrease in CTPA utilization (from 17.5 to 16.2 CT pulmonary angiographic examinations per 1,000 admissions before and after CDS, respectively, P = .003) was observed.

conclusionsWhen CDS recommendations were followed, the yield of CTPA was significantly higher than when clinicians overrode CDS alerts. In addition, point-of-order CDS to reduce unnecessary CTPA in hospitalized patients resulted in a significant decrease in CTPA utilization after CDS implementation, with a modest although nonsignificant increase in CTPA yield.

Indexed as

Computed Tomography AngiographyDecision Support Systems, ClinicalPulmonary EmbolismAgedCross-Sectional StudiesFemaleHospitalizationHumansMaleMiddle AgedRetrospective Studiesclinical decision supportCT pulmonary angiographyPulmonary embolismquality improvement

Identifiers

PMID39662713
PMCPMC12738065

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.