Evidence map›Paper›PMID 39662506›Full record

ArticleNature2025

Skin autonomous antibody production regulates host-microbiota interactions.

Inta Gribonika, Victor I Band, Liang Chi, Paula Juliana Perez-Chaparro, Verena M Link, Eduard Ansaldo, Cihan Oguz, Djenet Bousbaine, Michael A Fischbach, Yasmine Belkaid

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Multi-omics profiling of chronic immune-mediated skin diseases: SKINERGY protocol and strategic evaluation.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Observational
  5. Regulatory T cells in the skin: Origin, function, and plasticity.JID innovations : skin science from molecules to population health · 2026
    Review
  6. Article
  7. Article
  8. Germinal center responses at barrier organ sites.Current opinion in immunology · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Hidden immune memory niches in inflammatory skin diseases.bioRxiv : the preprint server for biology · 2026
    Article
  14. Review
  15. Skin bacteriota ameliorates androgenetic alopecia via harmonizing skin immuno inflammatory balance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  16. Article
  17. Review
  18. The multilayered identity of B cell memory.Cellular & molecular immunology · 2026
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Inta GribonikaMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. inta.gribonika@nih.gov.ORCID 0000-0002-5694-1315
Victor I BandMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Liang ChiMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Paula Juliana Perez-ChaparroNIAID Microbiome Program, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Verena M LinkMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-3207-312X
Eduard AnsaldoMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-7128-3373
Cihan OguzIntegrated Data Sciences Section, Research Technologies Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.ORCID 0000-0002-2860-3546
Djenet BousbaineDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0003-2683-9544
Michael A FischbachDepartment of Bioengineering, Stanford University, Stanford, CA, USA.ORCID 0000-0003-3079-8247
Yasmine BelkaidMetaorganism Immunity Section, Laboratory of Host Immunity and Microbiome, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. ybelkaid@niaid.nih.gov.ORCID 0000-0001-9962-3571

Funding

Building the foundations of commensal vaccinesR01AI175642 · NIAID · STANFORD UNIVERSITY · PI MICHAEL ANDREW FISCHBACH · 2022 to 2026
$3.8M
NIAID NIH HHS R01 AI175642
6 · The paper itself

Abstract

The microbiota colonizes each barrier site and broadly controls host physiology

Indexed as

Antibody FormationHost Microbial InteractionsMicrobiotaSkinAnimalsFemaleGerminal CenterImmunoglobulin GLangerhans CellsLymph NodesMaleMiceMice, Inbred C57BLSymbiosisT Follicular Helper CellsT-Lymphocytes, RegulatoryImmunoglobulin G

Identifiers

PMID39662506
PMCPMC11864984

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.