Evidence map›Paper›PMID 39662168›Full record

ArticlePregnancy hypertension2025

Inpatient versus outpatient management of gestational hypertension or preeclampsia without severe features.

Blake Neuburg, Meghan Gallagher, Melodee Liegl, Amy Y Pan, Anna Palatnik

Abstract readComparative Study
In one paragraph

Article in Pregnancy hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Blake NeuburgDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Meghan GallagherDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Melodee LieglDepartment of Pediatrics, Division of Quantitative Health Services, Medical College of Wisconsin, Milwaukee, WI, USA.
Amy Y PanDepartment of Pediatrics, Division of Quantitative Health Services, Medical College of Wisconsin, Milwaukee, WI, USA.
Anna PalatnikDepartment of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Medical College of Wisconsin, Milwaukee, WI, USA; Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI, USA. Electronic address: apalatnik@mcw.edu.

Funding

Reducing the risk of chronic hypertension and improving vascular function following preeclampsiaR01HD112930 · NICHD · MEDICAL COLLEGE OF WISCONSIN · PI Anna Palatnik · 2024 to 2026
$1.9M
Intensive postpartum antihypertensive treatment to improve women's cardiovascular healthR34HL165013 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI PALATNIK, ANNA · 2023 to 2025
$648k
NHLBI NIH HHS R34 HL165013NICHD NIH HHS R01 HD112930
6 · The paper itself

Abstract

objectiveTo comparematernal and neonatal outcomes in patients diagnosed with gestational hypertension or preeclampsia without severe features by outpatient versus inpatient management. MATERIALS AND

methodsThis was a single center, retrospective, cohort study of patients with hypertensive disorder of pregnancy (HDP) before 37 weeks' gestation from January 2014 to March 2022. Patients were triaged to inpatient or outpatient management at the discretion of their obstetrician. Patients with an initial presentation of severe features were excluded. Bivariate and multivariate analyses were used to compare the primary outcome, severe maternal morbidity (SMM) as defined by one or more of the 21 CDC maternal morbidity identifiers, and the secondary outcomes of maternal ICU admission, development of severe features, placental abruption, time from diagnosis to giving birth, preterm birth < 37 weeks, low birthweight (<2500 g), 5-minute Apgar score < 7, and stillbirth.

resultsA total of 272 patients met the inclusion criteria with 229 (84.2 %) being managed outpatient and 43 (15.8 %) managed inpatient. In univariate analysis, outpatient management was associated with lower incidence of SMM, an increased interval from diagnosis of HDP to giving birth, an increased interval to onset of severe features, and a lower incidence of maternal ICU admission. In multivariate analysis, outpatient management remained associated with lower odds of SMM, (aOR 0.18, 95 % CI 0.05-0.59) and improved neonatal outcomes with lower incidence of 5-minute APGAR score less than 7 (aOR 0.32, 95 % CI 0.13-0.82), low birth weight (aOR 0.37 95 % CI 0.17-0.79), and preterm birth (aOR 0.31, 95 % CI 0.15-0.67).

conclusionOutpatient management of HDP was associated with lower rates of SMM and adverse maternal and neonatal outcomes. While not all confounding factors were measured, the clinical decision regarding HDP management settings was associated with good diagnostic capability.

Indexed as

Ambulatory CareHospitalizationHypertension, Pregnancy-InducedPre-EclampsiaAdultFemaleHumansInfant, NewbornInpatientsOutpatientsPregnancyPregnancy OutcomeRetrospective StudiesGestational hypertensionInpatientOutpatientPreeclampsiaPregnancy

Identifiers

PMID39662168
PMCPMC11890927

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