Evidence map›Paper›PMID 39661797›Full record

ArticleBrazilian oral research2024

In vitro reduction of enamel erosion by sugarcane-derived cystatin associated with sodium trimetaphosphate.

Carolina Ruis Ferrari, Karolyne Sayuri de Araujo Kitamoto, Vinicius Taioqui Pelá, Éven Akemi Taira, Tamara Teodoro Araújo, Larissa Tercilia Grizzo Thomassian, Flávio Henrique-Silva, Juliano Pelim Pessan, Marília Afonso Rabelo Buzalaf

Abstract readEvaluation Study
In one paragraph

Article in Brazilian oral research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carolina Ruis FerrariUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0002-3997-043X
Karolyne Sayuri de Araujo KitamotoUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0003-2569-2624
Vinicius Taioqui PeláUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0001-7933-4422
Éven Akemi TairaUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0003-0853-1335
Tamara Teodoro AraújoUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0002-7560-9051
Larissa Tercilia Grizzo ThomassianUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0002-1469-5224
Flávio Henrique-SilvaUniversidade Federal de São Carlos - UFSCar, Department of Genetics and Evolution, São Carlos, SP, Brazil.ORCID http://orcid.org/0000-0003-3329-4597
Juliano Pelim PessanUniversidade Estadual Paulista - Unesp, School of Dentistry, Department of Preventive and Restorative Dentistry, Araçatuba, SP, Brazil.ORCID http://orcid.org/0000-0002-1550-3933
Marília Afonso Rabelo BuzalafUniversidade de São Paulo - USP, Bauru School of Dentistry, Department of Biological Sciences, Bauru, SP, Brazil.ORCID http://orcid.org/0000-0002-5985-3951

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The objective of this in vitro study was to assess the efficacy of CaneCPI-5, either alone or in combination with various concentrations of sodium trimetaphosphate (TMP) in protecting against initial enamel erosion. A total of 135 bovine enamel specimens were prepared and categorized into nine groups (n/group=15) according to the following treatments: Deionized water; Commercial solution (Elmex Erosion ProtectionTM); 0.1 mg/mL CaneCPI-5; 0.5% TMP; 1.0% TMP; 3.0% TMP; 0.1 mg/mL CaneCPI-5+0.5% TMP; 0.1 mg/mL CaneCPI-5+1.0%TMP; and 0.1 mg/mL CaneCPI-5+3.0%TMP. The specimens were treated with the respective solutions for 2 h, followed by acquired enamel pellicle formation for 2 h and exposure to 0.65% citric acid (CA) for 1 min. These procedures were repeated once a day for three consecutive days. Demineralization was assessed by the percentage change in surface hardness (%CSH) and calcium release into CA, analyzed by the Arsenazo III method. The data were evaluated using Kruskal-Wallis/Dunn's tests. Regarding %CSH, CaneCPI-5+3.0%TMP was the most effective treatment when compared to the CaneCPI-5 group alone. As for calcium release into CA, the CaneCPI-5+0.5% TMP and CaneCPI-5 groups (both with lower calcium release) did not significantly differ from the commercial solution. In conclusion, combination of CaneCPI-5 with TMP enhances the protective potential against initial enamel erosion in vitro.

Indexed as

Dental EnamelPolyphosphatesSaccharumTooth ErosionAnimalsCalciumCattleCitric AcidHardness TestsMaterials TestingReference ValuesReproducibility of ResultsStatistics, NonparametricSurface PropertiesTime FactorsTooth DemineralizationCalciumCitric AcidPolyphosphatestrimetaphosphoric acid

Identifiers

PMID39661797
PMCPMC11654876

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.