Evidence map›Paper›PMID 39661715›Full record

ArticleACS applied bio materials2025

Dual Thermo- and pH-Responsive Polymer Nanoparticle Assemblies for Potential Stimuli-Controlled Drug Delivery.

Sára Pytlíková, Rafal Konefał, Robert Pola, Alena Braunová, Volodymyr Lobaz, Miroslav Šlouf, Hynek Beneš, Daniil Starenko, Kateřina Běhalová, Marek Kovář and 3 more

Abstract read
In one paragraph

Article in ACS applied bio materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Stimuli-Responsive Supramolecular Biomaterials for Cancer Theranostics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sára PytlíkováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.
Rafal KonefałInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0003-4568-4891
Robert PolaInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0003-0025-2016
Alena BraunováInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.
Volodymyr LobazInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0003-0479-2837
Miroslav ŠloufInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0003-1528-802X
Hynek BenešInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0002-6861-1997
Daniil StarenkoInstitute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 00, Czech Republic.
Kateřina BěhalováInstitute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 00, Czech Republic.
Marek KovářInstitute of Microbiology, Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 00, Czech Republic.ORCID 0000-0002-6602-1678
Tomáš EtrychInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0001-5908-5182
Richard LagaInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0001-5420-2407
Michal PecharInstitute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 00, Czech Republic.ORCID 0000-0002-4507-1801

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of stimuli-responsive drug delivery systems enables targeted delivery and environment-controlled drug release, thereby minimizing off-target effects and systemic toxicity. We prepared and studied tailor-made dual-responsive systems (thermo- and pH-) based on synthetic diblock copolymers consisting of a fully hydrophilic block of poly[

Indexed as

Antibiotics, AntineoplasticBiocompatible MaterialsDoxorubicinDrug Delivery SystemsNanoparticlesPolymersCell SurvivalDrug LiberationDrug Screening Assays, AntitumorHumansHydrogen-Ion ConcentrationMaterials TestingParticle SizeSurface PropertiesTemperatureAntibiotics, AntineoplasticBiocompatible MaterialsDoxorubicinPolymersdrug delivery systemspH-sensitive polymersRAFT polymerizationself-assembling block copolymersthermoresponsive polymers

Identifiers

PMID39661715
PMCPMC11752510

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.