Evidence map›Paper›PMID 39661447›Full record

ArticleJournal of magnetic resonance imaging : JMRI2025

Free-Breathing Ungated Radial Simultaneous Multi-Slice Cardiac T1 Mapping.

Johnathan V Le, Jason K Mendes, Konstantinos Sideris, Erik Bieging, Spencer Carter, Josef Stehlik, Edward V R DiBella, Ganesh Adluru

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Johnathan V LeUtah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-3361-7691
Jason K MendesUtah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.
Konstantinos SiderisDepartment of Cardiology, University of Utah, Salt Lake City, Utah, USA.
Erik BiegingDepartment of Cardiology, University of Utah, Salt Lake City, Utah, USA.
Spencer CarterDepartment of Cardiology, University of Utah, Salt Lake City, Utah, USA.
Josef StehlikDepartment of Cardiology, University of Utah, Salt Lake City, Utah, USA.
Edward V R DiBellaUtah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.
Ganesh AdluruUtah Center for Advanced Imaging Research (UCAIR), Department of Radiology and Imaging Sciences, University of Utah, Salt Lake City, Utah, USA.

Funding

Improved Imaging of Fibrosis in Atrial FibrillationR01HL162353 · NHLBI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI DIBELLA, EDWARD VR, ELHABIAN, SHIREEN YOUSSEF · 2022 to 2025
$2.9M
Siemens MAGNETOM Prisma 3T MRI scannerS10OD018482 · OD · UNIVERSITY OF UTAH · PI PARKER, DENNIS L · 2015 to 2015
$1.2M
Improved cardiac T1 reactivity measures for gadolinium-free MRI assessment of ischemic heart diseaseR56HL162699 · NHLBI · UNIVERSITY OF UTAH · PI ADLURU, GANESH · 2022 to 2022
$489k
CLC NIH HHS R01HL162353CLC NIH HHS R56HL162699CLC NIH HHS S10OD018482-01NHLBI NIH HHS R01 HL162353NHLBI NIH HHS R56 HL162699NIH HHS S10 OD018482
6 · The paper itself

Abstract

backgroundModified Look-Locker imaging (MOLLI) T1 mapping sequences are acquired during breath-holding and require ECG gating with consistent R-R intervals, which is problematic for patients with atrial fibrillation (AF). Consequently, there is a need for a free-breathing and ungated framework for cardiac T1 mapping. PURPOSE: To develop and evaluate a free-breathing ungated radial simultaneous multi-slice (SMS) cardiac T1 mapping (FURST) framework. STUDY TYPE: Retrospective, nonconsecutive cohort study. POPULATION: Twenty-four datasets from 17 canine and 7 human subjects (4 males, FIELD STRENGTH/SEQUENCE: Pre- and post-contrast T1 mapping with the free-breathing and ungated SMS inversion recovery sequence with gradient echo readout and with conventional MOLLI sequences at 1.5 T and 3.0 T. ASSESSMENT: MOLLI and FURST were acquired in all subjects, and American Heart Association (AHA) segmentation was used for segment-wise analysis. Pre-contrast T1, post-contrast T1, and ECV were analyzed using correlation and Bland-Altman plots in 13 canines and 7 human subjects. T1 difference box plots for repeated acquisitions in four canine subjects were used to assess reproducibility. The PIQUE image quality metric was used to evaluate the perceptual quality of T1 maps. STATISTICAL TESTS: Paired t-tests were used for all comparisons between FURST and MOLLI, with

resultsThere were no significant differences between FURST and MOLLI pre-contrast T1 reproducibility (

conclusionsFURST had similar quality pre-contrast T1, post-contrast T1, and ECV maps and similar reproducibility compared to MOLLI. LEVEL OF EVIDENCE: 3 TECHNICAL EFFICACY: 1.

Indexed as

Atrial FibrillationHeartMagnetic Resonance ImagingAdultAgedAlgorithmsAnimalsDogsFemaleHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMaleMiddle AgedReproducibility of ResultsRespirationcardiac T1 mappingfree‐breathingmodel‐based reconstructionungated

Identifiers

PMID39661447
PMCPMC12063770

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.