Evidence map›Paper›PMID 39661326›Full record

ArticleSchizophrenia bulletin2025

The Negative Symptom Inventory-Psychosis Risk (NSI-PR): Psychometric Validation of the Final 11-Item Version.

Gregory P Strauss, Elaine F Walker, Nathan T Carter, Lauren Luther, Vijay A Mittal

Abstract readValidation Study
In one paragraph

Article in Schizophrenia bulletin, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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  3. Humanizing "multimodal" digital phenotyping of serious mental illness.Journal of psychopathology and clinical science · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gregory P StraussDepartment of Psychology, University of Georgia, Athens, GA 30602, United States.
Elaine F WalkerDepartment of Psychology, Emory University, Atlanta, GA 30322, United States.ORCID 0000-0002-9798-8101
Nathan T CarterDepartment of Psychology, Michigan State University, East Lansing, MI 48824, United States.
Lauren LutherDepartment of Psychology, University of Georgia, Athens, GA 30602, United States.
Vijay A MittalDepartment of Psychology, Northwestern University, Evanston, IL 60208, United States.ORCID 0000-0001-9017-5119

Funding

Prodromal Inventory for Negative Symptoms (PINS): A Development and Validation StudyR01MH116039 · NIMH · UNIVERSITY OF GEORGIA · PI MITTAL, VIJAY A, STRAUSS, GREGORY P · 2019 to 2023
$3.1M
2/3 Community psychosis risk screening: An instrument development studyR01MH112545 · NIMH · NORTHWESTERN UNIVERSITY · PI MITTAL, VIJAY A · 2017 to 2021
$1.2M
NIMH NIH HHS R01 MH112545NIMH NIH HHS R01-MH112545NIMH NIH HHS R01 MH116039NIMH NIH HHS R01-MH116039
6 · The paper itself

Abstract

background and hypothesesThe lack of psychometrically validated assessment tools designed specifically to assess negative symptoms in individuals at clinical high risk (CHR) for psychosis represents a significant barrier to the early identification and prevention of psychosis. To address this need, the Negative Symptom Inventory-Psychosis Risk (NSI-PR) was developed based on the iterative, data-driven approach recommended by the National Institute of Mental Health consensus conference on negative symptoms. STUDY

designThis manuscript reports the results of the second study phase that psychometrically validates the final 11-item version of the scale in data collected across 3 sites. A total of 222 participants (144 CHR and 78 clinical help-seeking controls) completed the NSI-PR, 1 week of ecological momentary assessment (EMA), and additional convergent and discriminant validity measures. STUDY

resultsStructural analyses replicated the previously reported strong fit for the 5-factor (anhedonia, avolition, asociality, alogia, and blunted affect) and hierarchical structures (2 super-ordinate dimensions and 5 lower-level domains). The 5 domains and 2 dimensions generally demonstrated good internal consistency, temporal stability, and interrater reliability. Convergent validity was demonstrated in relation to the 16-item beta version of the NSI-PR, Structured Interview for Psychosis-risk Syndromes negative subscale, Global Functioning Scale social and role, and EMA measures. Discriminant validity was supported by low correlations with positive, disorganized, and general psychiatric symptoms.

conclusionsFindings indicate the final 11-item version of the NSI-PR has sound psychometric properties. The scale, which is designed specifically for CHR individuals, is brief and appropriate for use in research and clinical contexts. Accompanying training materials have been developed to support its use in multisite trials.

Indexed as

AnhedoniaPsychiatric Status Rating ScalesPsychometricsPsychotic DisordersAdolescentAdultEcological Momentary AssessmentFemaleHumansMaleProdromal SymptomsReproducibility of ResultsRiskYoung Adultclinical interviewearly identificationprodromerating scaleultra-high risk

Identifiers

PMID39661326
PMCPMC12414547

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.