Evidence map›Paper›PMID 39661249›Full record

ReviewDermatology and therapy2025

Sexual Dysfunction in Chronic Urticaria: A Systematic Review.

Sarah E Park, Elaine Ma, Caitlyn Dagenet, Maria A Aleshin, Heather M Holahan, Vivian Y Shi, Jennifer L Hsiao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sarah E ParkDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Elaine MaKeck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA.
Caitlyn DagenetUniversity of Arizona College of Medicine, Tucson, AZ, USA.
Maria A AleshinDepartment of Dermatology, Stanford University School of Medicine, Redwood City, CA, USA.
Heather M HolahanDivision of Dermatology, University of California Los Angeles, Los Angeles, CA, USA.
Vivian Y ShiDepartment of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
Jennifer L HsiaoDepartment of Dermatology, University of Southern California, 1441 Eastlake Ave, Ezralow Tower, Suite 5301, Los Angeles, CA, 90033-9174, USA. j.hsiao.publications@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic urticaria (CU) is frequently a debilitating skin condition characterized by recurrent and spontaneous wheal and flares with significant impact on quality of life. This systematic review examines the impact of CU on sexual health.

methodsA systematic review using PubMed, Embase, Web of Science, and Cochrane library databases was conducted for articles on sexual health in chronic urticaria.

resultsThe database search produced 741 articles, of which 14 articles met inclusion criteria. Study design, patient demographics, disease characteristics, measures used to assess sexuality or sexual function, and study results were independently extracted for each article by two researchers. Any discrepancies were resolved to consensus by a third reviewer. Sexual dysfunction was common in patients with CU and its severity is associated with increased disease activity and poor disease control.

conclusionSexual dysfunction is common in patients with CU, and it negatively affects their quality of life (QoL), body image, sleep quality, and mental health. Incorporating sexual health assessments into CU trials will allow for valuable insights into efficacy of study medications on this important QoL domain. Increased awareness of sexual impairment in CU is needed to provide comprehensive care.

Indexed as

Chronic spontaneous urticariaChronic urticariaSexual dysfunctionSexual healthSexual impairmentSystematic review

Identifiers

PMID39661249
PMCPMC11785859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.