Evidence map›Paper›PMID 39661247›Full record

ArticleLa Radiologia medica2025

The CT collateral map: collateral perfusion estimation and baseline lesion assessment after acute anterior circulation ischemic stroke.

Hee Jong Ki, Hong Gee Roh, Jin Tae Kwak, In Seong Kim, Jeong Jin Park, Yoo Sung Jeon, Hyun Yang, Sumin Jung, Ji Sung Lee, Hyun Jeong Kim

Abstract read
In one paragraph

Article in La Radiologia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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  3. Observational
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Hee Jong KiDepartment of Neurosurgery, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-0914-5516
Hong Gee RohDepartment of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-0227-0971
Jin Tae KwakDeepClue Inc., Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0003-0287-4097
In Seong KimDeepClue Inc., Daejeon, Republic of Korea.
Jeong Jin ParkDepartment of Neurology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-9325-164X
Yoo Sung JeonDepartment of Neurosurgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0003-4163-9639
Hyun YangSchool of Electrical Engineering, Korea University, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0006-3395-3918
Sumin JungSchool of Electrical Engineering, Korea University, Seoul, Republic of Korea.ORCID http://orcid.org/0009-0003-2556-8399
Ji Sung LeeClinical Research Center, Asan Institute for Life Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.ORCID http://orcid.org/0000-0001-8194-3462
Hyun Jeong KimDeepClue Inc., Daejeon, Republic of Korea. mskendy429@gmail.com.ORCID http://orcid.org/0000-0002-1312-3080

Funding

Korea Institute of Startup and Entrepreneurship Development 20228485National Research Foundation of Korea RS-2023-00248375National Research Foundation of Korea RS-2023-00252980National Research Foundation of Korea RS-2023-00266130
6 · The paper itself

Abstract

purposeTo investigate the clinical feasibility of a CT collateral map compared with an MRA collateral map, focusing on collateral perfusion (CP) estimation and baseline lesion assessment in acute ischemic stroke (AIS). MATERIALS AND

methodsThis retrospective analysis used selected data from a prospectively collected database. We generated CT collateral maps derived from CT perfusion, encompassing images of arterial, capillary, early venous (CMEV), late venous, and delay phases. Three raters assessed CP scores from MRA and CT collateral maps and CMEV lesion volumes. Lesion volumes of baseline diffusion-weighted imaging (bDWI) and cerebral blood flow rate (CBF) < 30% were automatically measured by the software. The agreement between MRA and CT collateral maps in CP estimation and the correlation between lesion volumes with a CBF < 30% and the CMEV for bDWI lesion volumes were analyzed.

resultsOne-hundred ten patients (mean age ± standard deviation, 71 ± 14; 60 women) with AIS due to steno-occlusion of the internal carotid and/or middle cerebral arteries were included. The agreement between the MRA and CT collateral maps in CP grading was excellent (weighted κ = 0.93; 95% CI, 0.90-0.97). The concordance correlation coefficients (CCCs) of the CBF < 30% and CMEV for bDWI lesion volumes were 0.76 (95% CI, 0.60-0.91) and 0.97 (0.95-0.98), respectively.

conclusionThe clinical feasibility of the CT collateral map is demonstrated by its significant correlation with the MRA collateral map in CP estimation and baseline lesion assessment.

Indexed as

Cerebrovascular CirculationCollateral CirculationIschemic StrokeTomography, X-Ray ComputedAgedAged, 80 and overCerebral AngiographyDiffusion Magnetic Resonance ImagingFeasibility StudiesFemaleHumansMagnetic Resonance AngiographyMaleMiddle AgedRetrospective StudiesCerebrovascular disordersCollateral circulationDiagnostic imagingIschemiaPerfusion imagingStroke

Identifiers

PMID39661247
PMCPMC11870971

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.