Evidence map›Paper›PMID 39661237›Full record

Observational studyTechniques in coloproctology2024

Outcomes of loop ileostomy after rectal resection for cancer: A prospective observational multicenter snapshot study from Multidisciplinary Italian Study group for STOmas (MISSTO).

F Ferrara, G Rizzo, A Bondurri, C Forni, G Anania, A Anastasi, G L Baiocchi, L Boccia, D Cassini, M Catarci and 43 more

Registry-linked trialAbstract readMulticenter StudyObservational Study
PubMed Publisher
In one paragraph

Observational study in Techniques in coloproctology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06824623 (Multicenter Prospective Observational Study to Prevent the Risk of REadmission and DEhydration of Patients With ileoSTOmy in Elective Colorectal Surgery), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06824623 recruitingnot on this mapstarted 2025, after this paper: background citation

Multicenter Prospective Observational Study to Prevent the Risk of REadmission and DEhydration of Patients With ileoSTOmy in Elective Colorectal Surgery

Typeobservational_patient_registrySponsorMultidisciplinary Italian Study group for STOmas (MISSTO)Ran2025 to 2026Enrolled300ConditionsIleostomy - Stoma, Colorectal Surgery, Dehydration
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
  5. Article
  6. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors.

F FerraraDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), Unit of General and Oncologic Surgery, "Paolo Giaccone" Hospital, University of Palermo, Via Alfonso Giordano, 90127, Palermo, Italy. francesco.ferrara08@unipa.it.ORCID 0000-0002-8208-1945
G RizzoUnit of Digestive and Colorectal Surgery, Ospedale Isola Tiberina Gemelli Isola, Rome, Italy.
A BondurriUnit of General Surgery 1, Luigi Sacco University Hospital, ASST FBF-Sacco, Milan, Italy.ORCID 0000-0002-6521-5876
C ForniNursing and Allied Profession Research Unit, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
G AnaniaUnit of General Surgery 1, Arcispedale Sant'Anna, Ferrara, Italy.
A AnastasiUnit of General Surgery, San Giovanni Di Dio Hospital, Florence, Italy.
G L BaiocchiUnit of General Surgery, ASST Cremona, Cremona, Italy.
L BocciaUnit of General and Minimally Invasive Surgery, "Carlo Poma" Hospital, ASST Mantova, Mantova, Italy.
D CassiniUnit of General Surgery, Legnano Hospital, Legnano, Italy.
M CatarciUnit of General Surgery, Sandro Pertini Hospital, Rome, Italy.
G CestaroUnit of General Surgery, San Antonio Abate Hospital, Gallarate, Italy.
N CillaraUnit of General Surgery, Santissima Trinità Hospital, Cagliari, Italy.
F CobellisUnit of General Surgery, Casa Di Cura "Prof. Dott. Luigi Cobellis", Vallo Della Lucania, Italy.
R De LucaDepartment of Surgical Oncology, IRCCS Istituto Tumori "Giovanni Paolo II", Bari, Italy.
P De NardiUnit of Gastrointestinal Surgery, San Raffaele Scientific Institute, Milan, Italy.
S DeiddaUnit of Coloproctology, Cagliari University Hospital, Cagliari, Italy.
D DeloguUnit of Surgical Pathology, Sassari University Hospital, Sassari, Italy.
M FediUnit of General Surgery, San Jacopo Hospital, Pistoia, Italy.
M C GiuffridaUnit of General and Oncologic Surgery, S. Croce E Carle Hospital, Cuneo, Italy.
U GrossiDiSCOG Department, Unit of General Surgery 2, Treviso Regional Hospital, University of Padova, Padua, Italy.
H ImpellizzeriUnit of General Surgery, Pederzoli Hospital, Peschiera Del Garda, Italy.
A LangoneUnit of General and Oncologic Surgery, S. Paolo Hospital, Savona, Italy.
A LaurettaUnit of Oncologic Surgery for Sarcomas, Rare and Multi-Visceral Tumors, CRO IRCCS, Aviano, Italy.
F Lo CelsoUnit of General Surgery, Cattinara Hospital, Trieste, Italy.
A MaffioliUnit of General Surgery 1, Luigi Sacco University Hospital, ASST FBF-Sacco, Milan, Italy.
M ManigrassoUnit of Endoscopic Surgery, Federico II University Hospital, Naples, Italy.
C MarafanteUnit of General Surgery, Ospedale Degli Infermi, Rivoli, Italy.
L MaranoUnit of Surgical Oncology, Le Scotte University Hospital, University of Siena, Siena, Italy.
P MarinelloUnit of General Surgery, Central Hospital, Bolzano, Italy.
P MassuccoUnit of General and Oncologic Surgery, AO Ordine Mauriziano, Turin, Italy.
D MerliniUnit of General Surgery, Garbagnate Hospital, ASST Rhodense, Garbagnate Milanese, Italy.
L MorelliUnit of General Surgery, Pisa University Hospital, Pisa, Italy.
M MozzonUnit of General Surgery, ASUFC Udine Hospital, Udine, Italy.
D P PafundiUnit of General Surgery 2, Gemelli IRCCS University Hospital, Rome, Italy.
F PataDepartment of Pharmacy, Health and Nutritional Sciences, University of Calabria, Cosenza, Italy.
G PellinoUnit of Colorectal Surgery, Luigi Vanvitelli University of Campania, Primo Policlinico, Naples, Italy.
R PeltriniUnit of General and Oncologic Surgery, Federico II University Hospital, Naples, Italy.
A PetrinaUnit of General Surgery, Perugia University Hospital, Perugia, Italy.
D PiazzaUnit of General and Oncologic Surgery, ARNAS Garibaldi, Catania, Italy.
C RabuiniUnit of General Surgery, Principe di Piemonte Hospital, Senigallia, Italy.
A ResendizUnit of General Surgery, San Luigi Gonzaga Hospital, Turin, Italy.
B SalmasoUnit of General Surgery, Santa Maria Della Misericordia Hospital, Rovigo, Italy.
M SantarelliUnit of General and Emergency Surgery, AOU Città Della Salute E Della Scienza, Turin, Italy.
G SenaDipartimento Specialità Chirurgiche, Pugliese-Ciaccio Hospital, Catanzaro, Italy.
L SiragusaUOSD Chirurgia Generale E Dell'apparato Digerente, Tor Vergata University Hospital, Rome, Italy.
N TaminiUnit of General Surgery, San Gerardo Hospital, Monza, Italy.
V TondoloUnit of Digestive and Colorectal Surgery, Ospedale Isola Tiberina Gemelli Isola, Rome, Italy.
R TutinoUnit of General and Emergency Surgery, Paolo Giaccone University Hospital, Palermo, Italy.
A VannelliUnit of General Surgery, Valduce Hospital, Como, Italy.
M VeltriUnit of General Surgery, San Jacopo Hospital, Pistoia, Italy.
L VincentiUnit of General Surgery, Azienda Ospedaliero Universitaria Consorziale Policlinico, Bari, Italy.
D PariniUnit of General Surgery, Santa Maria Della Misericordia Hospital, Rovigo, Italy.
MISSTO Snapshot Study Collaborative Group

Funding

Università degli Studi di Palermo ProgRic2023-Mis1.1.a
6 · The paper itself

Abstract

backgroundDiverting ileostomy is a common procedure in rectal cancer surgery, but it is sometimes associated with a nonnegligible rate of complications. The primary aim of this study was to analyze the incidence and types of stoma-related complications for ileostomy creation after rectal cancer resection. The secondary aims were to report the indications, the technical details, and the efficacy of stoma care provided by ostomy nurses.

methodsFrom 15 February to 31 December 2022, consecutive patients who underwent protective ileostomy after anterior rectal cancer resection were enrolled for prospective data collection at 45 Italian colorectal surgery centers. Univariate and multivariate analyses were performed to evaluate factors that influenced the occurrence of stoma-related complications.

resultsIn all, 287 patients were enrolled in the analysis. The short- and long-term postoperative stoma-related morbidity rates were 33.8% and 29.62%, respectively. The most frequent complications were dehydration (17.77%), peristomal skin dermatitis (13.59%), mucocutaneous separation (8.36%), and stoma retraction (4.18%). At the end of follow-up (median time 9 months), the overall stoma closure rate was 83.97% (241 patients), with a median time to stoma closure of 146 days (range 9-483 days). On multivariate analysis, the presence of a stoma nurse was a significant protective factor against stoma-related complications.

conclusionsThis study demonstrated that the creation of a protective ileostomy is associated to a nonnegligible rate of short-term and long-term postoperative stoma-related morbidity, higher than 25%. The most frequent complication is dehydration, and the presence of stoma-specialized nurses seems to be a protective factor for stoma-related complications. Moreover, more than 15% of protective stomas were not closed at the end of follow-up.

Indexed as

IleostomyPostoperative ComplicationsRectal NeoplasmsAdultAgedAged, 80 and overFemaleHumansIncidenceItalyMaleMiddle AgedProctectomyProspective StudiesSurgical StomasTreatment OutcomeColorectalIleostomyOstomyRectal cancer

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