Evidence map›Paper›PMID 39661218›Full record

ReviewNano convergence2024

Nano-fluorescence imaging: advancing lymphatic disease diagnosis and monitoring.

Chae Yeon Han, Sang-Hun Choi, Soo-Hyang Chi, Ji Hyun Hong, Young-Eun Cho, Jihoon Kim

Abstract readReview
In one paragraph

Review in Nano convergence, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chae Yeon HanSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
Sang-Hun ChoiSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
Soo-Hyang ChiSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
Ji Hyun HongDepartment of Radiation Oncology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, 06591, South Korea.
Young-Eun ChoDepartment of Food and Nutrition, Andong National University, Andong, 36729, South Korea.
Jihoon KimSchool of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea. jihoonkim@cau.ac.kr.ORCID http://orcid.org/0000-0001-7091-8050

Funding

Chung-Ang University Graduate Research Scholarship in 2024Ministry of Science and ICT, South Korea RS-2023-00210162Ministry of Science and ICT, South Korea RS-2024-00406723
6 · The paper itself

Abstract

The lymphatic system plays a crucial role in maintaining physiological homeostasis and regulating immune responses. Traditional imaging modalities such as magnetic resonance imaging, computerized tomography, and positron emission tomography have been widely used to diagnose disorders in the lymphatic system, including lymphedema, lymphangioma, lymphatic metastasis, and Castleman disease. Nano-fluorescence technology has distinct advantages-including naked-eye visibility, operational simplicity, portability of the laser, and real-time visibility-and serves as an innovative alternative to traditional imaging techniques. This review explores recent advancements in nano-fluorescence imaging aimed at enhancing the resolution of lymphatic structure, function, and immunity. After delineating the fundamental characteristics of lymphatic systems, it elaborates on the development of various nano-fluorescence systems (including nanoparticles incorporating fluorescent dyes and those with intrinsic fluorescence) while addressing key challenges such as photobleaching, limited tissue penetration, biocompatibility, and signal interference from biomolecules. Furthermore, this review highlights the clinical applications of nano-fluorescence and its potential integration into standard diagnostic protocols. Ongoing advancements in nanoparticle technology underscore the potential of nano-fluorescence to revolutionize the diagnosis and treatment of lymphatic disease.

Indexed as

Fluorescence imagingLymph nodeNano-fluorescence

Identifiers

PMID39661218
PMCPMC11635084

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.