Evidence map›Paper›PMID 39661216›Full record

ArticleResearch on child and adolescent psychopathology2025

Common Genetic and Environmental Contributions to Anxiety Sensitivity, Anxiety, and Cognitive Symptoms of Eating Disorders in Adolescence.

Rachel Smail-Crevier, Gerome Breen, Thalia C Eley, Lance M Rappaport

Abstract readTwin Study
In one paragraph

Article in Research on child and adolescent psychopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rachel Smail-CrevierDepartment of Psychology, University of Windsor, Windsor, ON, N9B 3P4, Canada. smailcr@uwindsor.ca.ORCID 0000-0003-0783-5310
Gerome BreenInstitute of Psychiatry, Psychology & Neuroscience, Social Genetic and Developmental Psychiatry Centre, Kings College London, Memory Lane, London, England, SE5.ORCID 0000-0003-2053-1792
Thalia C EleyInstitute of Psychiatry, Psychology & Neuroscience, Social Genetic and Developmental Psychiatry Centre, Kings College London, Memory Lane, London, England, SE5.ORCID 0000-0001-6458-0700
Lance M RappaportDepartment of Psychology, University of Windsor, Windsor, ON, N9B 3P4, Canada.ORCID 0000-0002-3265-0898

Funding

Medical Research Council MR/M021475/1Medical Research Council MR/V012878/1
6 · The paper itself

Abstract

Anxiety sensitivity may be associated with both anxiety and eating disorder symptoms, which could contribute to the frequent comorbidity of both syndromes. This study examined the common (i.e., correlated) genetic and environmental contributions to anxiety sensitivity, cognitive symptoms of eating disorder severity, and anxiety symptoms to understand their co-occurrence in adolescence. This study analyzed data from the Twins Early Development Study. When twins were 16 years old (N = 5,111 pairs), they self-reported anxiety sensitivity via the Child Anxiety Sensitivity Index and cognitive symptoms of eating disorder severity via four items from the Eating Disorder Diagnostic Scale. Parents reported adolescent anxiety symptoms via the Anxiety Related Behaviour Questionnaire. Common genetic and non-shared environmental factors contributed to phenotypic correlations among cognitive symptoms of eating disorders. Genetic and nonshared environmental influences contributed to anxiety sensitivity and a latent variable of cognitive symptoms of eating disorder severity. Genetic, shared-, and nonshared- environmental influences contributed to anxiety symptoms. Common genetic and nonshared environmental influences contributed to anxiety sensitivity and anxiety symptoms, as well as anxiety sensitivity and cognitive symptoms of eating disorder severity. However, there was no evidence of common genetic or environmental contributions to anxiety symptoms and cognitive symptoms of eating disorder severity. This study implicates anxiety sensitivity as a potential cognitive process associated with both anxiety symptoms and cognitive symptoms of eating disorders.

Indexed as

AnxietyCognitionFeeding and Eating DisordersGene-Environment InteractionAdolescentHumansSeverity of Illness IndexAdolescentAnxietyAnxiety sensitivityBehavioral geneticsEating disorder symptoms

Identifiers

PMID39661216
PMCPMC7618485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.