ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2025
Impact of new-onset atrial fibrillation in patients with ST-segment elevation myocardial infarction.
Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Left atrial-ventricular coupling index associated with new-onset atrial fibrillation in ST-segment elevation myocardial infarction patients.BMC cardiovascular disorders · 2025Article
- How to manage new-onset atrial fibrillation following ST-segment elevation myocardial infarction.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Atrial Fibrillation as an Independent Predictor of Myocardial Ischemia.Medicina (Kaunas, Lithuania) · 2025Article
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Authors and funding
15 authors.
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Abstract
backgroundNew-onset atrial fibrillation (NOAF) complicating ST-segment elevation myocardial infarction (STEMI) remains clinically challenging. The aim of this study was to assess the incidence of NOAF, identify risk factors for the development of atrial fibrillation (AF), and analyze the impact on patient care, therapy, and outcomes during long-term follow-up.
methodsThis retrospective single-center study reviewed consecutive patients undergoing coronary angiography (CAG) for acute STEMI between May 2015 and September 2023. Patients were stratified in NOAF, defined as AF diagnosed during the index hospitalization or within 12 months of follow-up, AF prior to the hospitalization for STEMI, and patients with no AF.
resultsWe analyzed 1301 consecutive patients undergoing CAG for STEMI. NOAF was detected in 112 patients (9.8%), and 68 patients (5.2%) had prior AF. NOAF patients were 74% males, with a mean age of 69 ± 11 years. During a median follow-up of 683 days, the rates of stroke were 10% in patients with NOAF compared to 3.8% (p = 0.001) in patients without AF. Major bleeding occurred in 7% vs. 1.7%, p = 0.001, and death in 16% vs. 6.8%, p < 0.001 of patients with NOAF vs. no AF.
conclusionNOAF was detected in almost 1 out of 10 STEMI patients and was associated with a higher rate of stroke, major bleeding, and death as in patients with no AF and with similar rates compared with prior AF. Future studies assessing optimal anticoagulation therapy in this challenging patient population are warranted.
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