Evidence map›Paper›PMID 39661011›Full record

ArticleJournal of diabetes investigation2025

Glucagon-like pepetide-1 receptor agonist suggests novel therapeutic options for hypothalamic obesity.

Wanlu Ma, Bo Zhang, Xiaoping Chen

Abstract readEditorial
In one paragraph

Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wanlu MaDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing, China.
Bo ZhangDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing, China.
Xiaoping ChenDepartment of Endocrinology, China-Japan Friendship Hospital, Beijing, China.ORCID https://orcid.org/0000-0002-5894-2661

Funding

National High Level Hospital Clinical Research Funding 2022-NHLHCRF-LX-02-0101National High Level Hospital Clinical Research Funding and Elite Medical Professionals Project of China-Japan Friendship Hospital ZRJY2021-QM02Young Elite Scientist Sponsorship Program by Bast BYESS2023173
6 · The paper itself

Abstract

We briefly summarizes the mechanism of GLP-1RA therapy in HO both in rodents and in humans. We also summarized the clinical trials and case reports of GLP-1RA therapy in HO, especially the more and more often used semaglutide. We are hoping the therapy of GLP-1RA in HO will arouse more attention from clinicians in the future.

Indexed as

Glucagon-Like Peptide-1 Receptor AgonistsHypothalamic DiseasesObesityAnimalsGlucagon-Like Peptide 1Glucagon-Like PeptidesHumansSemaglutideGlucagon-Like Peptide 1Glucagon-Like Peptide-1 Receptor AgonistsGlucagon-Like PeptidesSemaglutide

Identifiers

PMID39661011
PMCPMC11871401

What OpenQuestion holds

Texttitle and abstract
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.