Evidence map›Paper›PMID 39661010›Full record

ReviewExpert review of gastroenterology & hepatology2024

Overcoming the effects of increasing antimicrobial resistance on

David Yates Graham, Theodore Rokkas

Abstract readReview
In one paragraph

Review in Expert review of gastroenterology & hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Challenges and Prospects for Eradication ofPathogens (Basel, Switzerland) · 2025
    Review
  5. Antibiotics (Basel, Switzerland) · 2025
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

David Yates GrahamDepartment of Medicine, Michael E. DeBakey Veterans, Affairs Medical Center and Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-6908-8317
Theodore RokkasGastroenterology Clinic, Henry Dunant Hospital, Athens, Greece.ORCID 0000-0001-6475-3026

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Hashem B El-Serag · 2001 to 2026
$28.3M
NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

introductionResistance to the antibiotics used to treat AREAS COVERED: This review covers current aspects management of the response to the effects of antimicrobial resistance on H. pylori therapy. EXPERT OPINION: The prevalence of antimicrobial resistance to H. pylori is increasing and must now be integrated into management of the infection. Bacterial factors responsible for resistance include mutations, efflux pumps, and biofilm formation. Societal factors include overuse and misuse of antibiotics, including in the therapy of H. pylori infections. H. pylori infections should be managed as an infectious disease based on the principles of antimicrobial stewardship which should be incorporated into ongoing community-based and hospital programs of antibiotic stewardship to provide up-to-date advice regarding susceptibility and locally optimized best treatment practices (i.e. advice on which drugs, doses, formulation, frequency of administration, etc. The infection would best be managed in concert with infectious disease especially in asymptomatic patients. Gastroenterology's input remains critical for management of complications of the infection such as peptic ulcer disease.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipDrug Resistance, BacterialHelicobacter InfectionsHelicobacter pyloriDrug Therapy, CombinationHumansTreatment OutcomeAnti-Bacterial Agentsantibioticsantimicrobial stewardshipHelicobacter pyloriresistancetreatment

Identifiers

PMID39661010
PMCPMC12035676

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.