Evidence map›Paper›PMID 39660506›Full record

ArticleOrganic letters2024

A Catalytic, Enantioselective Sulfamate Tethered

Harshit Joshi, Abhijit Manna, Someshwar Nagamalla, Annu Anna Thomas, Shyam Sathyamoorthi

Abstract read
In one paragraph

Article in Organic letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Transformation of Linear AlkenylChemistry (Basel, Switzerland) · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Harshit JoshiDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.
Abhijit MannaDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.
Someshwar NagamallaDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.ORCID 0000-0003-4430-6936
Annu Anna ThomasDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.
Shyam SathyamoorthiDepartment of Medicinal Chemistry, University of Kansas, Lawrence, Kansas 66047, United States.ORCID 0000-0003-4705-7349

Funding

Tethered aza-Wacker Technology for Complex Antibiotic AssemblyR35GM142499 · NIGMS · UNIVERSITY OF KANSAS LAWRENCE · PI SATHYAMOORTHI, SHYAM · 2021 to 2025
$1.9M
NIGMS NIH HHS R35 GM142499
6 · The paper itself

Abstract

We show the first examples of enantioselective cyclization reactions of tethered sulfamates onto pendant α,β-unsaturated esters, ketones, and thioesters. This reaction is promoted by a new chiral bifunctional guanidine catalyst and is operationally very simple. A variety of primary sulfamates and sulfamides were examined, and in many cases, products were delivered in excellent yields and enantiomeric ratios. With secondary sulfamates, kinetic resolutions were possible. The product oxathiazinanes are very useful chiral synthons.

Identifiers

PMID39660506
PMCPMC11662505

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.